ArticleNature communications2022
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
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15 citing papers in PubMed, 27 citations in OpenAlex.
- Chromatin Accessibility Reveals Adaptive Regulatory Variation in a Keystone Freshwater Fish.Molecular ecology · 2026Article
- Habitat Shifts and Conservation Challenges of Falconidae Under Climate Change in Northwestern China.Animals : an open access journal from MDPI · 2026Article
- Genetic legacy and recent cross of two ancient lineages underlie the rebound of the world's rarest primate.Science advances · 2026Article
- Evolution and Climate Adaptation in Eurasian Gyrfalcon Populations.Ecology and evolution · 2026Article
- Homeostasis of glucose and lipid metabolism during physiological responses to a simulated hypoxic high altitude environment.Nature communications · 2025Article
- Acute hypoxia suppresses blood glycolysis in saker falcons (Zoological research · 2025Article
- The Vulpes vulpes montana genome provides insights into high-altitude adaptation mechanisms of the Vulpes species.Communications biology · 2025Article
- Article
- Crop rotation increases Tibetan barley yield and soil quality on the Tibetan Plateau.Nature food · 2025Article
- Land Use and Climate Change Accelerate the Loss of Habitat and Ecological Corridor to Reeves's Pheasant (Ecology and evolution · 2024Article
- Genomic structural variation is associated with hypoxia adaptation in high-altitude zokors.Nature ecology & evolution · 2024Article
- Genetic analysis of Saker Falcon (Biodiversity data journal · 2024Article
- The Tibetan Antelope Population Depends on Lakes on the Tibetan Plateau.Animals : an open access journal from MDPI · 2023Article
- Phylogenomic insights into the polyphyletic nature of Altai falcons within eastern sakers (Falco cherrug) and the origins of gyrfalcons (Falco rusticolus).Scientific reports · 2023Article
- The metabolic adaptation in wild vertebrates via omics approaches.Life metabolism · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
20 authors at 9 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during cold adaptation, and how genomic mutations in non-coding regions regulate gene expression under hypoxia and intense UV environment, remain largely unknown. Here, we assemble a high-quality saker falcon genome and resequence populations across Eurasia. We identify female-biased hybridization with Arctic gyrfalcons in the last glacial maximum, that endowed eastern sakers with alleles conveying larger body size and changes in fat metabolism, predisposing their QTP cold adaptation. We discover that QTP hypoxia and UV adaptations mainly involve independent changes in non-coding genomic variants. Our study highlights key roles of gene flow from Arctic relatives during QTP hypothermia adaptation, and cis-regulatory elements during hypoxic response and UV protection.
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