Evidence map›Paper›PMID 36302018›Full record

ArticleScience (New York, N.Y.)2022

Microbial metabolites damage DNA.

Jens Puschhof, Cynthia L Sears

Abstract readComment
PubMed Publisher
In one paragraph

Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Microorganisms · 2025
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Jens PuschhofMicrobiome and Cancer Division, German Cancer Research Center, Heidelberg, Germany.
Cynthia L SearsDepartments of Medicine and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
German Cancer Research Center · DEJohns Hopkins Medicine · US

Funding

Cancer Research UK 27140
6 · The paper itself

Abstract

Unexpected members of the gut microbiota produce diverse host cell genotoxins.

Indexed as

Colorectal NeoplasmsDNA DamageGastrointestinal MicrobiomeMorganella morganiiMutagensAnimalsHumansMiceMutagens

Identifiers

PMID36302018
OpenAlexW4307412650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.