ArticlePloS one2022
Task-based profiles of language impairment and their relationship to cognitive dysfunction in Parkinson's disease.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Animal fluency in people with Parkinson's disease: Item-based performance before and after deep brain stimulation surgery.Journal of neuropsychology · 2026Article
- Language dysfunction as a primary feature of cognitive decline in neurological populations.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Domain-driven verbal and non-verbal dissociations in cognition and social cognition in Parkinson's disease.Frontiers in psychology · 2026Article
- Language skills in Parkinson's disease: state of the art.Dementia & neuropsychologia · 2026Review
- Subitem-level multi-scale assessment and machine learning for three-class cognitive status classification in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Neural basis of dysexecutive and visuospatial impairments in Parkinson's disease with MCI: a task-based fNIRS study.NPJ Parkinson's disease · 2025Article
- Long-term dopaminergic therapy improves spoken language in de-novo Parkinson's disease.Journal of neurology · 2025Observational
- Sex Differences in the Speech of Persons With and Without Parkinson's Disease.American journal of speech-language pathology · 2024Article
- Effects of Rehabilitation Training on Cognitive Function in Parkinson's Disease with Subjective Cognitive Decline.Neuropsychiatric disease and treatment · 2024Article
- Language impairment in Parkinson's disease: fMRI study of sentence reading comprehension.Frontiers in aging neuroscience · 2023Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveParkinson's Disease (PD) is associated with both motor and non-motor problems, such as cognitive impairment. Particular focus in this area has been on the relationship between language impairment and decline in other cognitive functions, with the literature currently inconclusive on how the nature and degree of language impairment relate to cognition or other measures of disease severity. In addition, little information is available on how language problems identified in experimental task set-ups relate to competency in self-generated language paradigms such as picture description, monologues or conversations. This study aimed to inform clinical management of language impairment in PD by exploring (1) language performance across a range of experimental as well as self-generated language tasks, (2) how the relationship between these two aspects might be affected by the nature of the cognitive and language assessment; and (3) to what degree performance can be predicted across the language tasks.
methods22 non-demented people with PD (PwPD) and 22 healthy control participants performed a range of cognitive and language tasks. Cognitive tasks included a screening assessment in addition to tests for set shifting, short term memory, attention, as well as letter and category fluency. Language was investigated in highly controlled grammar tasks as well as a Sentence Generation and a Narrative.
resultsThe study highlighted impaired ability in set-shifting and letter fluency in the executive function tasks, and a higher rate of grammatical and lexical errors across all language tasks in the PD group. The performance in the grammar task was linked to set shifting ability, but error rates in Sentence Generation and Narrative were independent of this. There was no relevant relationship between performances across the three language tasks.
conclusionsOur results suggest that there is a link between executive function and language performance, but that this is task dependent in non-demented PwPD. This has implications for the management of language impairment in PD, both for assessment and for designing effective interventions.
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