ArticleJournal of cardiovascular translational research2023
Learning the Hidden Signature of Fetal Arch Anatomy: a Three-Dimensional Shape Analysis in Suspected Coarctation of the Aorta.
Article in Journal of cardiovascular translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Roles and applications of artificial intelligence in fetal and placental MRI: a literature review.BMC pregnancy and childbirth · 2026Pooled it
- The Case for Interpretable Geometry: Statistical Shape Models vs. Curvature-Based Descriptors in Aortic Disease Classification.medRxiv : the preprint server for health sciences · 2026Article
- Prenatal ultrasound prediction of coarctation of the aorta: a nomogram for risk stratification.Pediatric radiology · 2025Article
- Fetal Cardiovascular Magnetic Resonance: History, Current Status, and Future Directions.Journal of magnetic resonance imaging : JMRI · 2025Review
- Understanding the hemodynamic changes in fetuses with coarctation of the aorta using a lumped model of fetal circulation.PLoS computational biology · 2025Article
- The onset of coarctation of the aorta before birth: Mechanistic insights from fetal arch anatomy and haemodynamics.Computers in biology and medicine · 2024Article
- Editorial: Case reports in general cardiovascular medicine: 2022.Frontiers in cardiovascular medicine · 2023Article
- The current state and potential innovation of fetal cardiac MRI.Frontiers in pediatrics · 2023Review
- Using computed tomography angiography and computational fluid dynamics to study aortic coarctation in different arch morphologies.Frontiers in pediatrics · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Neonatal coarctation of the aorta (CoA) is a common congenital heart defect. Its antenatal diagnosis remains challenging, and its pathophysiology is poorly understood. We present a novel statistical shape modeling (SSM) pipeline to study the role and predictive value of arch shape in CoA in utero. Cardiac magnetic resonance imaging (CMR) data of 112 fetuses with suspected CoA was acquired and motion-corrected to three-dimensional volumes. Centerlines from fetal arches were extracted and used to build a statistical shape model capturing relevant anatomical variations. A linear discriminant analysis was used to find the optimal axis between CoA and false positive cases. The CoA shape risk score classified cases with an area under the curve of 0.907. We demonstrate the feasibility of applying a SSM pipeline to three-dimensional fetal CMR data while providing novel insights into the anatomical determinants of CoA and the relevance of in utero arch anatomy for antenatal diagnosis of CoA.
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Registered trials
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