Evidence map›Paper›PMID 36301414›Full record

SynthesisPharmacoEconomics2023

Fenfluramine for Treating Dravet Syndrome: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.

Ben Wijnen, Willem Witlox, Robert Wolff, Debra Fayter, Bram Ramaekers, Thomas Otten, Steve Ryder, Pawel Posadzki, Gill Worthy, Lisa Stirk and 3 more

Open access · hybridAbstract readSystematic ReviewNetwork Meta-Analysis
PubMed Publisher
In one paragraph

Synthesis in PharmacoEconomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Ben WijnenDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), P. Debyelaan 25, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Willem WitloxDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), P. Debyelaan 25, PO Box 5800, 6202 AZ, Maastricht, The Netherlands. willem.witlox@mumc.nl.ORCID 0000-0003-1007-4284
Robert WolffKleijnen Systematic Reviews Ltd, York, UK.
Debra FayterKleijnen Systematic Reviews Ltd, York, UK.
Bram RamaekersDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), P. Debyelaan 25, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Thomas OttenDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), P. Debyelaan 25, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Steve RyderKleijnen Systematic Reviews Ltd, York, UK.
Pawel PosadzkiKleijnen Systematic Reviews Ltd, York, UK.
Gill WorthyKleijnen Systematic Reviews Ltd, York, UK.
Lisa StirkKleijnen Systematic Reviews Ltd, York, UK.
Nigel ArmstrongKleijnen Systematic Reviews Ltd, York, UK.
Jos KleijnenCenter of Economic Evaluation and Machine Learning, Trimbos Institute (Netherlands Institute of Mental Health and Addiction), Utrecht, The Netherlands.
Manuela JooreDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+ (MUMC+), P. Debyelaan 25, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Kleijnen Systematic Reviews (United Kingdom) · GBMaastricht University Medical Centre · NLTrimbos Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fenfluramine, tradename Fintepla

Indexed as

CannabidiolEpilepsies, MyoclonicAdolescentBayes TheoremChildCost-Benefit AnalysisHumansProspective StudiesQuality-Adjusted Life YearsQuality of LifeRandomized Controlled Trials as TopicRetrospective StudiesState MedicineTechnology Assessment, BiomedicalCannabidiol

Identifiers

PMID36301414
OpenAlexW4307426601

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.