Evidence map›Paper›PMID 36301410›Full record

ArticleObesity surgery2022

Delayed Gastric Emptying After Sleeve Gastrectomy Is Associated with Poor Weight Loss.

Anagi Chethana Wickremasinghe, Yazmin Johari, Cheryl Laurie, Kalai Shaw, Julie Playfair, Paul Beech, Helen Yue, Louise Becroft, Geoffrey Hebbard, Kenneth S Yap and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obesity surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Anagi Chethana WickremasingheDepartment of Surgery, Central Clinical School, Alfred Centre, Monash University, Level 6, 99 Commercial Rd, VIC, 3004, Melbourne, Australia. anagi.wickremasinghe@monash.edu.ORCID 0000-0001-9876-7792
Yazmin JohariDepartment of Surgery, Central Clinical School, Alfred Centre, Monash University, Level 6, 99 Commercial Rd, VIC, 3004, Melbourne, Australia.
Cheryl LaurieDepartment of Surgery, Central Clinical School, Alfred Centre, Monash University, Level 6, 99 Commercial Rd, VIC, 3004, Melbourne, Australia.
Kalai ShawDepartment of Surgery, Central Clinical School, Alfred Centre, Monash University, Level 6, 99 Commercial Rd, VIC, 3004, Melbourne, Australia.
Julie PlayfairDepartment of Surgery, Central Clinical School, Alfred Centre, Monash University, Level 6, 99 Commercial Rd, VIC, 3004, Melbourne, Australia.
Paul BeechDepartment of Nuclear Medicine and PET, The Alfred Hospital, Melbourne, VIC, 3004, Australia.
Helen YueDepartment of Nuclear Medicine and PET, The Alfred Hospital, Melbourne, VIC, 3004, Australia.
Louise BecroftDepartment of Surgery, Central Clinical School, Alfred Centre, Monash University, Level 6, 99 Commercial Rd, VIC, 3004, Melbourne, Australia.
Geoffrey HebbardDepartment of Gastroenterology, Royal Melbourne Hospital and University of Melbourne, Parkville, VIC, 3050, Australia.
Kenneth S YapDepartment of Nuclear Medicine and PET, The Alfred Hospital, Melbourne, VIC, 3004, Australia.
Wendy BrownDepartment of Surgery, Central Clinical School, Alfred Centre, Monash University, Level 6, 99 Commercial Rd, VIC, 3004, Melbourne, Australia.
Paul BurtonDepartment of Surgery, Central Clinical School, Alfred Centre, Monash University, Level 6, 99 Commercial Rd, VIC, 3004, Melbourne, Australia.
The Alfred Hospital · AUMonash Alfred Psychiatry Research centre · AUThe Royal Melbourne Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntermediate to long-term weight regain is a major challenge following sleeve gastrectomy (SG). Physiological changes that mediate the extent of weight loss remain unclear. We aimed to determine if there were specific esophago-gastric transit and emptying alterations associated with weight regain. MATERIAL AND

methodsParticipants greater than 12 months post-SG were categorized into optimal (n = 29) and poor weight loss (PWL) (n = 72). All patients underwent a liquid contrast barium swallow demonstrating normal post-surgical anatomy and a protocolized nuclear scintigraphy designed specifically to characterize gastric emptying following SG.

resultsThe %total weight loss in the optimal group was 26.2 ± 10.5 vs. 14.3 ± 8.8% in the PWL group (p = 0.001). Scintigraphy showed PWL had relatively increased gastric emptying half-time (GE

conclusionGastric emptying half-times greater than 21 min appear to reliably correlate with poor weight loss following SG. Additionally, further elevations above 21 min in emptying half-time increase the risk of poor weight loss. We have shown nuclear scintigraphy represents a simple and accurate diagnostic tool in patients who experience poor weight loss after SG, provided substantially altered reporting references in interpreting nuclear scintigraphy are applied.

Indexed as

Gastric BypassGastroparesisObesity, MorbidGastrectomyGastric EmptyingHumansWeight GainWeight LossBariatric outcomeBariatric surgery mechanismClinical trialComplicationsDiagnostic testGastric emptyingNuclear scintigraphyPhysiological failurePhysiologyRefluxSleeveWeight regain

Identifiers

PMID36301410
PMCPMC9671974
OpenAlexW4307427219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.