Evidence map›Paper›PMID 36301353›Full record

ArticleBrain structure & function2023

The effects of vibration on the neuronal activity of lateral vestibular nuclei in unilaterally labyrinthectomized rats.

S H Sarkisyan, M H Danielyan, L V Darbinyan, K V Simonyan, V A Chavushyan

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Article in Brain structure & function, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

S H SarkisyanDepartment of Human and Animal Physiology, Yerevan State University, Yerevan, Armenia.
M H DanielyanHistochemistry and Electron Microscopy Lab, Orbeli Institute of Physiology NAS RA, Yerevan, Armenia.
L V DarbinyanSensorimotor Integration Lab, Orbeli Institute of Physiology NAS RA, Yerevan, Armenia.
K V SimonyanNeuroendocrine Relationships Lab, Orbeli Institute of Physiology NAS RA, Yerevan, Armenia. karensimonyan86@gmail.com.
V A ChavushyanNeuroendocrine Relationships Lab, Orbeli Institute of Physiology NAS RA, Yerevan, Armenia.
L. A. Orbeli Institute of Physiology NAS RA · AMYerevan State University · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unilateral labyrinthectomy causes distinct oculomotor and postural disorder syndromes that gradually deteriorate. Simultaneously, compensatory mechanisms for the suppression of pathological disorders were activated. The current study aimed to investigate the characteristics of impulse activity in the ipsilateral and contralateral neurons of the lateral vestibular nucleus of unilaterally labyrinthectomized rats during various periods of vibration exposure. A program analysis of the background impulse activity of the neurons in the right- and left-lateral vestibular nuclei of rats under normal condition and after right-sided labyrinthectomy was performed. The animals were subjected to different periods of vibration exposure 2 days after surgery (5-, 10-, and 15-day periods). A comparison of the characteristics of the background impulse activity of neurons in both nuclei of intact rats revealed an initial asymmetry in the values of the mean impulse frequency and coefficient of variation of interimpulse intervals. After 5 days of vibration exposure, the values of the mean impulse frequency of neurons in both Deiters' nuclei were almost equal in labyrinthectomized rats. The mean impulse frequency of neurons on the uninjured side was higher than that on the injured side on the days following vibration exposure. The characteristics and functional significance of the findings are discussed.

Indexed as

Ear, InnerVestibular NucleiAnimalsNeuronsRatsVibrationBackground impulse activityLabyrinthectomyLateral vestibular nucleiVestibular compensationVibration

Identifiers

PMID36301353
OpenAlexW4307431334

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.