Evidence map›Paper›PMID 36301040›Full record

SynthesisImmunity, inflammation and disease2022

Symptomatology, prognosis, and clinical findings of Monkeypox infected patients during COVID-19 era: A systematic-review.

Vikash Jaiswal, Priyanshu Nain, Dattatreya Mukherjee, Amey Joshi, Mittal Savaliya, Angela Ishak, Nitya Batra, Dipansha Maroo, Deepak Verma

Erratum issuedOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Immunity, inflammation and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 5 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 5 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Monkeypox-Induced Myocarditis: A Systematic Review.Current problems in cardiology · 2023
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Review
  7. Review
  8. Article
  9. Monkeypox Virus and Pregnancy.Journal of medical virology · 2025
    Review
  10. Mpox and oral health among children in Africa.Frontiers in oral health · 2025
    Article
  11. Article
  12. Poxviridae Pneumonia.Advances in experimental medicine and biology · 2024
    Review
  13. Article
  14. Article
  15. Corrigendum.Immunity, inflammation and disease · 2023
    Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Vikash JaiswalDepartment of Research, Larkin Community Hospital, South Miami, Florida, USA.ORCID 0000-0002-2021-1660
Priyanshu NainDepartment of Medicine, Maulana Azad Medical College, New Delhi, India.
Dattatreya MukherjeeDepartment of Medicine, Raiganj Government Medical College and Hospital, Raiganj, West Bengal, India.ORCID 0000-0001-7566-3843
Amey JoshiDepartment of Research, Larkin Community Hospital, South Miami, Florida, USA.
Mittal SavaliyaDepartment of Medicine, GMERS Medical College, Junagadh, Gujarat, India.ORCID 0000-0001-8095-6544
Angela IshakDepartment of Research, Larkin Community Hospital, South Miami, Fl, USA.ORCID 0000-0002-6789-5860
Nitya BatraDepartment of Medicine, Maulana Azad Medical College, New Delhi, India.
Dipansha MarooDepartment of Medicine, Maulana Azad Medical College, New Delhi, India.
Deepak VermaDepartment of Medicine, Janaki Medical College, Dhanusha, Nepal.
Larkin Community Hospital · USMaulana Azad Medical College · INJunagadh Agricultural University · INNepal Medical College Teaching Hospital · NPRaiganj University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe recent outbreak of Human Monkeypox (MPXV) in nonendemic regions of the world is of great concern.

objectiveWe aimed to systematically analyze the current epidemiology, clinical presentation, and outcomes of the Monkeypox virus.

methodSystematic literature was conducted in PubMed, Embase, Google Scholar, and Scopus using predefined MESH terms by using "AND" and "OR." The following search terms were used: Monkeypox [MeSH] OR "Monkeypox virus" [MeSH] OR "POX" OR "Monkeypox" AND "Outbreak" AND "Outcomes" from December 2019 till 14th June 2022 without restrictions of language.

resultsA total of 1074 (99.90%) patients tested positive for Monkeypox virus through RT-PCR while 1 (0.09) patient was suspected. There was a gender difference with male predominance (54.23% vs. 45.48%) compared with female patients. Mean age (±SD) of patients was 20.66 ± 16.45 years. The major symptoms were rash (100%), fever (96%), and other important symptoms were upper respiratory symptoms (97%), headache (95%), vomiting (95%), oral ulcers (96%), conjunctivitis (96%) and lymphadenopathy (85%). The average mean duration of treatment was 5 days, while the mean hospitalization duration was 13.3 ± 6.37 days. The outcome of 20 patients was available, 19 of 20 patients recovered fully from monkeypox, however, 1 patient was not able to survive resulting in death.

conclusionThe recent monkeypox virus outbreak has shown that the virus could transmit in ways that were not previously expected. Further research is needed to understand the possible outcomes and association with humans and their different organ systems.

Indexed as

COVID-19Mpox, MonkeypoxAdolescentAdultChildChild, PreschoolDisease OutbreaksFemaleHumansMaleMonkeypox virusPrognosisYoung Adultinfectionmonkeypox virusoutcomespathology

Identifiers

PMID36301040
PMCPMC9552975
OpenAlexW4304203538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.