ArticleActa bio-medica : Atenei Parmensis2022
Molecular epidemiology of SEN virus among blood donors and renal dialysis patients.
Article in Acta bio-medica : Atenei Parmensis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed, 1 citations in OpenAlex.
- Alteration of microbial composition in the skin and blood in vasculitis.Scientific reports · 2023Article
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe SEN virus (SEN-V) is a single-stranded circular, non-enveloped DNA virus that has been linked to blood transfusion and is thought to be a major cause of post-transfusion hepatitis. The two SENV types, SENV-H and SENV-D, are non-A to E hepatitis viruses in those who are infected. The purpose of this study is to find out how common SENV and its variations are among renal dialysis patients and healthy blood donors.
methodsThe study used a cross-sectional design, with 300 blood samples collected from KFMMC patients, 150 from healthy blood donors and 150 from renal dialysis patients, between January 2019 and January 2021. The samples were screened for the presence of SENV-D and SENV-H. using nested PCR.
resultsMolecular analysis of the SEN virus revealed that 9.3% of the samples (14 out of 150) tested positive for SEN virus infection in renal dialysis patients. The data from healthy donors revealed that 10% of the samples tested positive for the SEN virus (15 out of 150).
conclusionsThe presence of SEN-V in healthy blood donors and renal dialysis patients demonstrates the virus's blood-borne nature and emphasizes the dangers of blood-borne transmission.
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