Evidence map›Paper›PMID 36300226›Full record

ReviewActa bio-medica : Atenei Parmensis2022

Retrospective observational studies: Lights and shadows for medical writers.

Vincenzo De Sanctis, Ashraf T Soliman, Shahina Daar, Ploutarchos Tzoulis, Bernadette Fiscina, Christos Kattamis, International Network Of Clinicians For Endocrinopathies In Thalassemia And Adolescence Medicine Icet-A

Abstract readReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Evaluating the effect of two different training interventions on improving vaginal twin birth rates and provider confidence and knowledge levels: A pre- and post-intervention study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Observational
  5. Article
  6. READER'S FORUM.Korean journal of orthodontics · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Vehicle extrication in road traffic crashes: a descriptive analysis of an advanced medical rescue service in South Africa.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vincenzo De SanctisQuisisana Hospital, Ferrara. vdesanctis@libero.it.
Ashraf T SolimanPediatrics and Endocrinology Department of Pediatrics, Hamad Medical Center, Doha, Qatar and Department of Pediatrics, University of Alexandria, Alexandria, Egypt. atsoliman56@gmail.com.
Shahina DaarDepartment of Haematology, College of Medicine and Health Sciences, Sultan Qaboos University, Sultanate of Oman and Stellenbosch Institute for Advanced Study (STIAS), Wallenberg Research Centre at Stellenbosch University, Stellenbosch, South Africa. sf.daar@gmail.com.
Ploutarchos TzoulisConsultant Endocrinologist and Diabetologist, Whittington Hospital- UCL Medical School, London, UK. ptzoulis@yahoo.co.uk.
Bernadette FiscinaDepartment of Pediatrics, NYU School of Medicine, New York, NY, USA. bfiscina@yahoo.com.
Christos KattamisFirst Department of Paediatrics, National Kapodistrian University of Athens, Athens, Greece. christos.kattamis@gmail.com.
International Network Of Clinicians For Endocrinopathies In Thalassemia And Adolescence Medicine Icet-A. vdesanctis@libero.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A retrospective study (by definition non-interventional) is a purely observational review and/or reassessment of database records with the aim of analyzing previous events of interest. The ethical and scientific standards for conducting biomedical research with humans have been established in international guidelines. Nevertheless, the reporting of ethical considerations in human research is not yet agreed upon globally, although some progress has been made in recent years. If a study has been granted exemption from ethics approval, this should be indicated in the manuscript (including the reasons for the exemption) and, if formal review by an ethics committee is not available, a statement should be included indicating that the research was conducted according to the principles of the Declaration of Helsinki. Editors play an important role in adherence to these ethical requirements for all submitted and published research papers in their journals. This short review paper focuses on the main lights and shadows of ethical aspects for conducting retrospective observational studies in humans and implications for medical writers.

Indexed as

Biomedical ResearchMedical WritingHumansInformed ConsentRetrospective Studies

Identifiers

PMID36300226
PMCPMC9686178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.