Evidence map›Paper›PMID 36300221›Full record

ArticleActa bio-medica : Atenei Parmensis2022

Hospital acquired infections in COVID-19 patients in sub intensive care unit: analysis of two waves of admissions.

Silvana Castaldi, Pier Mario Perrone, Ester Luconi, Giuseppe Marano, Francesco Auxilia, Anna Maraschini, Patrizia Bono, Laura Alagna, Emanuele Palomba, Alessandra Bandera and 2 more

Open access · greenAbstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Factors behind Antibiotic Therapy: A Survey of Primary Care Pediatricians in Lombardy.International journal of environmental research and public health · 2024
    Article
  3. Vaccination Open Day: A Cross-Sectional Study on the 2023 Experience in Lombardy Region, Italy.International journal of environmental research and public health · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Silvana CastaldiDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore di Milano, Milan, Italy. silvana.castaldi@unimi.it.
Pier Mario Perronea:1:{s:5:"en_US";s:33:"Università degli studi di Milano";}. piermario.perrone@unimi.it.
Ester LuconiDepartment of Clinical Sciences and Community Health & DSRC, University of Milan, Milan, Italy. ester.luconi@unimi.it.
Giuseppe MaranoDepartment of Clinical Sciences and Community Health & DSRC, University of Milan, Milan, Italy. giuseppe.marano@unimi.it.
Francesco AuxiliaASST FBF e Sacco, Milan, Italy. francesco.auxilia@unimi.it.
Anna MaraschiniFondazione IRCCS Ca' Granda Ospedale Maggiore di Milano, Milan, Italy. anna.maraschini@policlinico.mi.it.
Patrizia BonoFondazione IRCCS Ca' Granda Ospedale Maggiore di Milano, Milan, Italy. patrizia.bono@policlinico.mi.it.
Laura AlagnaFondazione IRCCS Ca' Granda Ospedale Maggiore di Milano, Milan, Italy. laura.alagna@policlinico.mi.it.
Emanuele PalombaDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy. emanuele.palomba@unimi.it.
Alessandra BanderaFondazione IRCCS Ca' Granda Ospedale Maggiore di Milano, Milan, Italy; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. alessandra.bandera@unimi.it.
Patrizia BoracchiDepartment of Clinical Sciences and Community Health & DSRC, University of Milan, Milan, Italy. patrizia.boracchi@unimi.it.
Elia BiganzoliDepartment of Clinical Sciences and Community Health & DSRC, University of Milan, Milan, Italy. elia.biganzoli@unimi.it.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · ITASST Fatebenefratelli Sacco · ITBocconi University · ITOspedale San Giuseppe · ITUniversiti Malaysia Perlis · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThe pandemic caused by SARS-COV-2 has increased Semi-Intensive Care Unit (SICU) admission, causing an increase in healthcare-associated infection (HAI). Mostly HAI reveals the same risk factors, but fewer studies have analyzed the possibility of multiple coinfections in these patients. The study aimed was to identify patterns of co-presence of different species describing at the same time the association between such patterns and patient demographics and, finally, comparing the patterns between the two cohorts of COVID-19 patients admitted at Policlinico during the first wave and the second one).

methodsAll the patients admitted to SICUs during two COVID-19 waves, from March to June 2020 months and from October to December 2020, were screened following the local infection control surveillance program; whoever manifested fever has undergone on microbiological culture to detect bacterial species. Statistical analysis was performed to observe the existence of microbiological patterns through DBSCAN method.

results246 patients were investigated and 83 patients were considered in our study because they presented infection symptoms with a mean age of 67 years and 33.7% of female patients. During the first and second waves were found respectively 10 and 8 bacterial clusters with no difference regarding the most frequent species.

conclusionsThe results show the importance of an analysis which considers the risk factors for the possibility of co- and superinfection (such as age and gender) to structure a good prognostic tool to predict which patients will encounter severe coinfections during hospitalization.

Indexed as

CoinfectionCOVID-19Cross InfectionAgedFemaleHospitalizationHospitalsHumansIntensive Care UnitsRetrospective StudiesSARS-CoV-2

Identifiers

PMID36300221
PMCPMC9686160
OpenAlexW4307499110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.