Evidence map›Paper›PMID 36300184›Full record

ArticleFrontiers in medicine2022

Natural killer cell infusion for cytomegalovirus infection in pediatric patients with Wiskott-Aldrich syndrome following cord blood transplantation: A case report and literature review.

Yongwei Yue, Lijun Meng, Jing Ling, Liyan Fan, Yanlei Zhang, Yixin Hu, Alex H Chang, Shaoyan Hu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yongwei YueDepartment of Hematology & Oncology, Children's Hospital of Soochow University, Suzhou, China.
Lijun MengDepartment of Hematology & Oncology, Children's Hospital of Soochow University, Suzhou, China.
Jing LingDepartment of Hematology & Oncology, Children's Hospital of Soochow University, Suzhou, China.
Liyan FanDepartment of Hematology & Oncology, Children's Hospital of Soochow University, Suzhou, China.
Yanlei ZhangClinical Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Yixin HuDepartment of Hematology & Oncology, Children's Hospital of Soochow University, Suzhou, China.
Alex H ChangClinical Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Shaoyan HuDepartment of Hematology & Oncology, Children's Hospital of Soochow University, Suzhou, China.
Soochow University · CNShanghai Pulmonary Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NK cells have important functions in resisting cytomegalovirus infection, as they proliferate after viral infection and have certain immunological memory. Here, we report infusion of haploid donor-derived natural killer cells to treat two pediatric patients with Wiskott-Aldrich syndrome (WAS) who were infected with cytomegalovirus after cord blood transplantation (CBT), which successfully cleared the viral infection in both patients.

Indexed as

case reportcord blood transplantationcytomegalovirus infectionNK cell infusionWiskott-Aldrich syndrome

Identifiers

PMID36300184
PMCPMC9588986
OpenAlexW4303958773

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.