Evidence map›Paper›PMID 36299943›Full record

ReviewCureus2022

Obesity and Coronary Artery Disease: An Updated Systematic Review 2022.

Mohana Priya Manoharan, Rabab Raja, Aneeque Jamil, Denise Csendes, Sai Dheeraj Gutlapalli, Keerthana Prakash, Kiran Maee Swarnakari, Meena Bai, Darshi M Desai, Aditya Desai and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Association of maternal body mass index with hemodynamic and vascular alterations at 35-37 weeks' gestation.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Observational
  11. Observational
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. The signaling pathways in obesity-related complications.Journal of cell communication and signaling · 2024
    Review
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Mohana Priya ManoharanInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Rabab RajaMedicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Aneeque JamilInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Denise CsendesInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sai Dheeraj GutlapalliInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Keerthana PrakashInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Kiran Maee SwarnakariInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Meena BaiMedicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Darshi M DesaiDivision of Research & Academic Affairs, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Aditya DesaiInternal Medicine Clinical Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sai Sri PenumetchaGeneral Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Institute of Medical Sciences · INUniversity of California, Riverside · USCalifornia Institute of Behavioral Neurosciences and Psychology (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary goal is to identify the pathogenesis of cardiovascular illnesses in obese patients. Articles were extracted using the MeSH search approach from PubMed and Google Scholar databases. Inclusion and exclusion criteria were used, and duplicates were eliminated. Eight publications were finally included in this research study after two authors independently completed the quality check appraisal. Seven observational studies and one narrative review were found in our search. The publications evaluated the risk of coronary artery disease in metabolically healthy obese people with that of unhealthy obese adults and evaluated the effects of adipose tissue-mediated inflammation. Additionally, they offered several explanations for the obesity problem. Studies have indicated that adipocytokines and their pro-inflammatory cytokines have significantly affected the development of cardiovascular disease in obese subjects. The relationship between metabolically unhealthy people with increased risk for coronary artery disease (CAD) is unclear. It has also been shown that metabolically healthy obese persons are still at risk for developing coronary artery disease (CAD), as explained in certain studies in which inflammation plays a vital role in obese people. There hasn't been much data on the advantages of being physically active in overweight people, but obese people have to change their lifestyle as a first measure.

Indexed as

adipocytokinesbody mass indexcoronary artery diseasemetabolically healthy obesitymetabolic phenotypesmetabolic syndromeobesityobesity paradoxoverweightweight loss

Identifiers

PMID36299943
PMCPMC9588166
OpenAlexW4297002008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.