Evidence map›Paper›PMID 36299882›Full record

ArticleFrontiers in pharmacology2022

Ethanolic extract of

Joelle Mesmar, Rola Abdallah, Kamar Hamade, Serine Baydoun, Najlaa Al-Thani, Abdullah Shaito, Marc Maresca, Adnan Badran, Elias Baydoun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Polyphenol Diversity and Chemotype Variation inMolecules (Basel, Switzerland) · 2026
    Article
  4. Plants (Basel, Switzerland) · 2026
    Article
  5. Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  6. Therapeutic Insights intoPharmaceuticals (Basel, Switzerland) · 2025
    Article
  7. International journal of molecular sciences · 2025
    Article
  8. Extraction, purification and antioxidant activity of flavonoids fromFrontiers in bioengineering and biotechnology · 2025
    Article
  9. Anti-cancer agents in medicinal chemistry · 2025
    Article
  10. Review
  11. Article
  12. The Antioxidant Potential and Anticancer Activity ofAntioxidants (Basel, Switzerland) · 2024
    Article
  13. Determination ofPlants (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Review
  16. American journal of cancer research · 2024
    Article
  17. Effects ofMetabolites · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Joelle MesmarDepartment of Biology, American University of Beirut, Beirut, Lebanon.
Rola AbdallahDepartment of Biology, American University of Beirut, Beirut, Lebanon.
Kamar HamadeUMRT INRE 1158 BioEcoAgro, Laboratorie BIOPI, University of Picardie Jules Verne, Amiens, France.
Serine BaydounBreast Imaging Section, Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States.
Najlaa Al-ThaniResearch and Development Department, Barzan Holdings, Doha, Qatar.
Abdullah ShaitoBiomedical Research Center, College of Medicine, and Department of Biomedical Sciences at College of Health Sciences, Qatar University, Doha, Qatar.
Marc MarescaAix-Marseille University, CNRS, Centrale Marseille, iSm2, Marseille, France.
Adnan BadranDepartment of Nutrition, University of Petra, Amman, Jordan.
Elias BaydounDepartment of Biology, American University of Beirut, Beirut, Lebanon.
American University of Beirut · LBBiologie des Plantes et Innovation · FRCentre National de la Recherche Scientifique · FRCleveland Clinic · USPetra University · JOQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HYPOTHESIS/PURPOSE: The medicinal plant

methodsMTT, trans-well migration, and scratch assays were used to assess cell viability, invasion, or migration, respectively. Antioxidant potential was evaluated

resultsWe demonstrated that OSEE had potent radical scavenging activity

conclusionOur findings reveal that OSEE is a rich source of phytochemicals and has robust anti-breast cancer properties that significantly attenuate the malignant phenotype of MD-MB-231 cells, suggesting that

Indexed as

breast cancerherbal medicinemetastasisOriganum syriacum Loxidative stressphytochemical contentreactive oxygen speciesROS

Identifiers

PMID36299882
PMCPMC9589507
OpenAlexW4303980290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.