Evidence map›Paper›PMID 36299712›Full record

ArticleJournal of analytical methods in chemistry2022

Development of a Nanostructured Electrochemical Genosensor for the Detection of the K-ras Gene.

Luis Fernando Garcia-Melo, Miguel Morales-Rodríguez, Eduardo Madrigal-Bujaidar, Eduardo O Madrigal-Santillán, José Antonio Morales-González, Rosa Natali Pineda Cruces, Jorge Alfredo Campoy Ramírez, Pablo Damian-Matsumura, Alexandro Tellez-Plancarte, Nikola Batina and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of analytical methods in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Luis Fernando Garcia-MeloDivision de Ingeniería en Nanotecnología, Universidad Politécnica del Valle de México, Av. Mexiquense s/n esquina Av. Universidad Politécnica, Tultitlan Estado de México, CP 54910, Mexico.ORCID https://orcid.org/0000-0001-9477-4178
Miguel Morales-RodríguezDivision de Ingeniería en Nanotecnología, Universidad Politécnica del Valle de México, Av. Mexiquense s/n esquina Av. Universidad Politécnica, Tultitlan Estado de México, CP 54910, Mexico.ORCID https://orcid.org/0000-0003-1600-4914
Eduardo Madrigal-BujaidarLaboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Avenida Wilfrido Massieu s/n Col. Zacatenco Del. Gustavo A. Madero, CP 07738, Ciudad de México, Mexico.ORCID https://orcid.org/0000-0003-4256-1749
Eduardo O Madrigal-SantillánLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Unidad Casco de Santo Tomás, Plan de San Luis y Díaz Mirón, Ciudad de México, CP 11340, Mexico.ORCID https://orcid.org/0000-0001-7254-6350
José Antonio Morales-GonzálezLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Unidad Casco de Santo Tomás, Plan de San Luis y Díaz Mirón, Ciudad de México, CP 11340, Mexico.ORCID https://orcid.org/0000-0002-5980-0980
Rosa Natali Pineda CrucesLaboratorio de Nanotecnología e Ingeniería Molecular Área Electroquímica, Departamento de Química, CBI, Universidad Autónoma Metropolitana-Iztapalapa (UAM-I), Av. San Rafael Atlixco 186, Iztapalapa, CP 09340, México City, Mexico.ORCID https://orcid.org/0000-0002-6385-6119
Jorge Alfredo Campoy RamírezLaboratorio de Nanotecnología e Ingeniería Molecular Área Electroquímica, Departamento de Química, CBI, Universidad Autónoma Metropolitana-Iztapalapa (UAM-I), Av. San Rafael Atlixco 186, Iztapalapa, CP 09340, México City, Mexico.ORCID https://orcid.org/0000-0003-0558-6453
Pablo Damian-MatsumuraLaboratorio de Endocrinología Molecular, Departamento de Biología de la Reproducción, CBS, Universidad Autónoma Metropolitana-Iztapalapa (UAM-I), México City, Mexico.ORCID https://orcid.org/0000-0003-4815-2516
Alexandro Tellez-PlancarteLaboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Avenida Wilfrido Massieu s/n Col. Zacatenco Del. Gustavo A. Madero, CP 07738, Ciudad de México, Mexico.ORCID https://orcid.org/0000-0001-9541-1205
Nikola BatinaLaboratorio de Nanotecnología e Ingeniería Molecular Área Electroquímica, Departamento de Química, CBI, Universidad Autónoma Metropolitana-Iztapalapa (UAM-I), Av. San Rafael Atlixco 186, Iztapalapa, CP 09340, México City, Mexico.ORCID https://orcid.org/0000-0001-8217-8563
Isela Álvarez-GonzálezLaboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Avenida Wilfrido Massieu s/n Col. Zacatenco Del. Gustavo A. Madero, CP 07738, Ciudad de México, Mexico.ORCID https://orcid.org/0000-0003-4011-9121
Instituto Politécnico Nacional · MXUniversidad Autónoma Metropolitana · MXPolytechnic University of the Valley of Mexico · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the scientific literature, it has been documented that electrochemical genosensors are novel analytical tools with proven clinical diagnostic potential for the identification of carcinogenic processes due to genetic and epigenetic alterations, as well as infectious diseases due to viruses or bacteria. In the present work, we describe the construction of an electrochemical genosensor for the identification of the k12p.1 mutation; it was based on use of Screen-Printed Gold Electrode (SPGE), Cyclic Voltammetry (CV), and Atomic Force Microscopy (AFM), for the monitoring the electron transfer trough the functionalized nanostructured surface and corresponding morphological changes. The sensitivity of the genosensor showed a linear response for the identification of the k12p.1 mutation of the

Identifiers

PMID36299712
PMCPMC9592225
OpenAlexW4306660734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.