ArticlePhotoacoustics2022
High-speed wide-field photoacoustic microscopy using a cylindrically focused transparent high-frequency ultrasound transducer.
Article in Photoacoustics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Acquisition-inspired motion artifact modeling and degradation-consistent diffusion restoration in photoacoustic microscopy.Photoacoustics · 2026Article
- Fully integrated photoacoustic microscopy for multi-scale and longitudinal imaging in translational biomedical applications.Biomedical optics express · 2026Article
- Development of a Dual Photoacoustic-Ultrasound Imaging System: Current Status and Future Perspectives.Sensors (Basel, Switzerland) · 2026Review
- A handheld photoacoustic microscopic probe integrating a transparent ultrasound transducer and a fiber scanner.Nature communications · 2025Article
- GPU-accelerated volumetric-mosaic optical-resolution photoacoustic microscopy and quantifying tumor vasculature growth.Photoacoustics · 2025Article
- High-frequency (> 65 MHz) broadband transparent transducer with ultrathin gold electrode for dual-mode photoacoustic and laser-induced ultrasound microscopy.Photoacoustics · 2025Article
- A comprehensive review of high-performance photoacoustic microscopy systems.Photoacoustics · 2025Review
- Wavelength-time-division multiplexed fiber-optic sensor array for wide-field photoacoustic microscopy.Photoacoustics · 2025Article
- Transparent ultrasonic transducers based on relaxor ferroelectric crystals for advanced photoacoustic imaging.Nature communications · 2024Article
- Investigation of an Active Focusing Planar Piezoelectric Ultrasonic Transducer.Sensors (Basel, Switzerland) · 2024Article
- An ultrasensitive and broadband transparent ultrasound transducer for ultrasound and photoacoustic imaging in-vivo.Nature communications · 2024Article
- Sounding out the dynamics: a concise review of high-speed photoacoustic microscopy.Journal of biomedical optics · 2024Review
- Photoacoustic imaging plus X: a review.Journal of biomedical optics · 2024Review
- High speed innovations in photoacoustic microscopy.Npj imaging · 2024Review
- Tailored photoacoustic apertures with superimposed optical holograms.Biomedical optics express · 2023Article
- Broadband transparent ultrasound transducer with polymethyl methacrylate as matching layer forPhotoacoustics · 2023Article
- Editorial: Breaking the speed limits in photoacoustic microscopy.Photoacoustics · 2023Article
- Multiscale photoacoustic tomography using reversibly switchable thermochromics.Journal of biomedical optics · 2023Article
- Functional photoacoustic imaging: from nano- and micro- to macro-scale.Nano convergence · 2023Review
- Homogeneous-resolution photoacoustic microscopy for ultrawide field-of-view neurovascular imaging in Alzheimer's disease.Photoacoustics · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Combining focused optical excitation and high-frequency ultrasound detection, optical-resolution photoacoustic microscopy (OR-PAM) can provide micrometer-level spatial resolution with millimeter-level penetration depth and has been employed in a variety of biomedical applications. However, it remains a challenge for OR-PAM to achieve a high imaging speed and a large field of view at the same time. In this work, we report a new approach to implement high-speed wide-field OR-PAM, using a cylindrically-focused transparent ultrasound transducer (CFT-UT). The CFT-UT is made of transparent lithium niobate coated with indium-tin-oxide as electrodes. A transparent cylindrical lens is attached to the transducer surface to provide an acoustic focal line with a length of 9 mm. The excitation light can pass directly through the CFT-UT from the above and thus enables a reflection imaging mode. High-speed imaging is achieved by fast optical scanning of the focused excitation light along the CFT-UT focal line. With the confocal alignment of the optical excitation and acoustic detection, a relatively high detection sensitivity is maintained over the entire scanning range. The CFT-UT-based OR-PAM system has achieved a cross-sectional frame rate of 500 Hz over the scanning range of 9 mm. We have characterized the system's performance on phantoms and demonstrated its application on small animal models in vivo. We expect the new CFT-UT-based OR-PAM will find matched biomedical applications that need high imaging speed over a large field of view.
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