Evidence map›Paper›PMID 36299540›Full record

ArticleFrontiers in psychiatry2022

Cognitive behavioral therapy with adaptive virtual reality exposure vs. cognitive behavioral therapy with

Per Trads Ørskov, Mia Beck Lichtenstein, Mathias Torp Ernst, Iben Fasterholdt, Asge Frederik Matthiesen, Marco Scirea, Stephane Bouchard, Tonny Elmose Andersen

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05302518 (Virtual Reality for AnxIety Disorders - Randomized Controlled Trial), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05302518 nacompletednot on this map

Virtual Reality for AnxIety Disorders - Randomized Controlled Trial

TypeinterventionalSponsorRegion of Southern DenmarkRan2022 to 2025Enrolled80ConditionsSocial Anxiety, Social PhobiaArmsCognitive behavioral therapy with exposure in virtual reality, Cognitive behavioral therapy with exposure in vivo
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Per Trads ØrskovResearch Unit for Digital Psychiatry, Mental Health Services in the Region of Southern Denmark, Odense, Denmark.
Mia Beck LichtensteinResearch Unit for Digital Psychiatry, Mental Health Services in the Region of Southern Denmark, Odense, Denmark.
Mathias Torp ErnstResearch Unit for Digital Psychiatry, Mental Health Services in the Region of Southern Denmark, Odense, Denmark.
Iben FasterholdtCentre for Innovative Medical Technology, Odense University Hospital, Odense, Denmark.
Asge Frederik MatthiesenMaersk Mc-Kinney Moller Institute, University of Southern Denmark, Odense, Denmark.
Marco ScireaMaersk Mc-Kinney Moller Institute, University of Southern Denmark, Odense, Denmark.
Stephane BouchardDepartment of Psychoeducation and Psychology, University du Québec en Outaouais, Gatineau, QC, Canada.
Tonny Elmose AndersenDepartment of Psychology, University of Southern Denmark, Odense, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Social anxiety disorder (SAD) has a high prevalence and an early onset with recovery taking decades to occur. Current evidence supports the efficacy of cognitive behavioral therapy (CBT) with virtual reality (VR) exposure. However, the evidence is based on a sparse number of studies with predominantly small sample sizes. There is a need for more trials investigating the optimal way of applying VR based exposure for SAD. In this trial, we will test the efficacy of CBT with adaptive VR exposure allowing adjustment of the exposure based on real-time monitoring of the participants's anxiety level. Methods: The trial is a randomized controlled, assessor-blinded, parallel-group superiority trail. The study has two arms: (1) CBT including exposure Discussion: The study adds to the existing knowledge by assessing the efficacy of CBT with adaptive VR exposure. The study has high methodological rigor using a randomized controlled trial with a large sample size that includes follow-up data and validated measures for social anxiety outcomes. Clinical trial registration: ClinicalTrials.gov, identifier: NCT05302518.

Indexed as

cognitive behavioral therapyelectrodermal activityexposureheart ratemachine learningpsychophysiological measurementssocial anxietyvirtual reality

Identifiers

PMID36299540
PMCPMC9589352

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.