Evidence map›Paper›PMID 36299392›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2022

High-intensity aerobic interval training and resistance training are feasible in rectal cancer patients undergoing chemoradiotherapy: a feasibility randomized controlled study.

Elise Piraux, Gregory Reychler, David Vancraeynest, Xavier Geets, Daniel Léonard, Gilles Caty

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03252821 (Effects of High-intensity Training Compared to Resistance Training in Cancer Patients Undergoing Radiotherapy), which is not on this map. Cited by 15 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 7 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03252821 nacompletednot on this map

Effects of High-intensity Training Compared to Resistance Training in Cancer Patients Undergoing Radiotherapy

TypeinterventionalSponsorCliniques universitaires Saint-Luc- Université Catholique de LouvainRan2017 to 2019Enrolled78ConditionsProstate Cancer, Head and Neck Cancer, Rectum CancerArmsHigh-intensity interval training, Resistance training
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 7 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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  6. Rates of compliance and adherence to high-intensity interval training: a systematic review and Meta-analyses.The international journal of behavioral nutrition and physical activity · 2023
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  9. What works to engage cancer patients with fatigue in exercise: a scoping review of RCT-based interventions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Elise PirauxPôle de Neuro Musculo Skeletal Lab, Pôle de Pneumologie, ORL and Dermatologie, Institut de Recherche Expérimentale et Clinique, Clinical Neuroscience, Institute of Neurosciences, Université Catholique de Louvain, Haute Ecole Léonard de Vinci, PARNASSE-ISEI, Secteur de Kinésithérapie, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Gregory Reychler *Pôle de Pneumologie, ORL and Dermatologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Haute Ecole Léonard de Vinci, PARNASSE-ISEI, Secteur de Kinésithérapie, Service de Pneumologie, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
David VancraeynestPôle de Recherche Cardiovasculaire, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Service de Cardiologie, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Xavier GeetsMolecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Service de Radiothérapie Oncologique, Cliniques universitaires Saint-Luc, Brussels, Belgium.
Daniel LéonardService de Chirurgie et Transplantation Abdominale, Unité de Chirurgie Colorectale, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Gilles Caty *Clinical Neuroscience, Institute of Neurosciences, Université Catholique de Louvain, Service de Médecine Physique et Réadaptation, Cliniques Universitaires Saint-Luc,Brussels, Belgium.
Cliniques Universitaires Saint-Luc · BEHaute École Léonard de Vinci · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There has been growing evidence of the benefits of high-intensity aerobic interval training (HIIT) and resistance training (RES) for populations with cancer. However, these two modalities have not yet been performed alone in rectal cancer patients undergoing neoadjuvant chemoradiotherapy (NACR T). Therefore, this study aimed to determine the feasibility of HIIT and RES in rectal cancer patients undergoing NACR T. Materials and methods: Rectal cancer patients set to undergo NACRT were randomly assigned to HIIT intervention, RES intervention, or the usual care. Feasibility of HIIT and RES was assessed by measuring recruitment rate, adherence (retention rate, attendance rate, and exercise sessions duration and intensity), and adverse events. Endpoints (changes in fatigue, health-related quality of life, depression, daytime sleepiness, insomnia, sleep quality, functional exercise capacity, and executive function) were assessed at baseline and at week 5. Results: Among the 20 eligible patients, 18 subjects were enrolled and completed the study, yielding a 90% recruitment rate and 100% retention rate. Attendance at exercise sessions was excellent, with 92% in HIIT and 88% in RES. No exercise-related adverse events occurred. Conclusion: This study demonstrated that HIIT and RES are feasible in rectal cancer patients undergoing NACR T. Trial registration: www.clinicaltrials.gov, NCT03252821 (date of registration: March 30, 2017).

Indexed as

exercisehigh-intensity interval trainingneoadjuvant chemoradiotherapyrectal cancerresistance training

Identifiers

PMID36299392
PMCPMC9591035
OpenAlexW4284966361

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.