Evidence map›Paper›PMID 36299370›Full record

ArticleERJ open research2022

Prevalence and genetic basis of first-line drug resistance of

Jack Callum, Phuong T B Nguyen, Elena Martinez, Van-Anh T Nguyen, Frances Garden, Nhung V Nguyen, Thu-Anh Nguyen, Hoa B Nguyen, Son V Nguyen, Khanh B Luu and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Occurrence of multidrug-resistantVeterinary world · 2024
    Article
  4. Population-wide active case finding as a strategy to end TB.The Lancet regional health. Western Pacific · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 4 countries.

Jack CallumRoyal Prince Alfred Hospital, Camperdown, Australia.ORCID https://orcid.org/0000-0002-9666-9184
Phuong T B NguyenUniversity of Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0003-0755-6944
Elena MartinezWoolcock Institute of Medical Research, Sydney, Australia.
Van-Anh T NguyenNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Frances GardenUniversity of New South Wales, Sydney, Australia.
Nhung V NguyenVietnam National Lung Hospital, Hanoi, Vietnam.
Thu-Anh NguyenUniversity of Sydney, Sydney, Australia.
Hoa B NguyenVietnam National Lung Hospital, Hanoi, Vietnam.
Son V NguyenNational Tuberculosis Control Program, Hanoi, Vietnam.
Khanh B LuuWoolcock Institute of Medical Research, Sydney, Australia.
Jennifer HoWoolcock Institute of Medical Research, Sydney, Australia.
Nguyen N LinhGlobal Tuberculosis Program, World Health Organisation, Geneva, Switzerland.
Warwick J BrittonCentenary Institute, Camperdown, Australia.
Vitali SintchenkoUniversity of New South Wales, Sydney, Australia.
Greg J FoxRoyal Prince Alfred Hospital, Camperdown, Australia.
Guy B MarksWoolcock Institute of Medical Research, Sydney, Australia.ORCID https://orcid.org/0000-0002-8976-8053
The University of Sydney · AUWoolcock Institute of Medical Research · AUUNSW Sydney · AUCentenary Institute · AUHanoi Lung Hospital · VNInternational Union Against Tuberculosis and Lung Disease · FRNational Institute Of Hygiene And Epidemiology · VNVietnam Academy of Social Sciences · VNWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

Background and objective: Data on the prevalence of anti-tuberculous drug resistance and its association with genetic mutations in Methods: Patients ≥15 years in Ca Mau Province, Vietnam, were screened annually for tuberculosis between 2014 and 2017. Isolates underwent drug susceptibility testing (DST) using the breakpoint method. DNA was extracted and whole genome sequencing (WGS) was performed. Results: We identified 365 positive sputum cultures for Conclusion: The high burden of isoniazid resistance and the

Identifiers

PMID36299370
PMCPMC9589319
OpenAlexW4296063622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.