Evidence map›Paper›PMID 36299363›Full record

ArticleERJ open research2022

Obstructive sleep apnoea-related respiratory events and desaturation severity are associated with the cardiac response.

Salla Hietakoste, Tuomas Karhu, Saara Sillanmäki, Raquel Bailón, Thomas Penzel, Juha Töyräs, Timo Leppänen, Sami Myllymaa, Samu Kainulainen

Abstract read
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Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Salla HietakosteDept of Applied Physics, University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0001-5355-6203
Tuomas KarhuDept of Applied Physics, University of Eastern Finland, Kuopio, Finland.
Saara SillanmäkiDiagnostic Imaging Center, Kuopio University Hospital, Kuopio, Finland.
Raquel BailónAragón Institute of Engineering Research, University of Zaragoza, Zaragoza, Spain.
Thomas PenzelInterdisciplinary Sleep Medicine Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Juha TöyräsDept of Applied Physics, University of Eastern Finland, Kuopio, Finland.
Timo LeppänenDept of Applied Physics, University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0003-4017-821X
Sami MyllymaaDept of Applied Physics, University of Eastern Finland, Kuopio, Finland.
Samu KainulainenDept of Applied Physics, University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0003-2798-2115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obstructive sleep apnoea (OSA) causes, among other things, intermittent blood oxygen desaturations, increasing the sympathetic tone. Yet the effect of desaturations on heart rate variability (HRV), a simple and noninvasive method for assessing sympathovagal balance, has not been comprehensively studied. We aimed to study whether desaturation severity affects the immediate HRV. Methods: We retrospectively analysed the electrocardiography signals in 5-min segments (n=39 132) recorded during clinical polysomnographies of 642 patients with suspected OSA. HRV parameters were calculated for each segment. The segments were pooled into severity groups based on the desaturation severity ( Results: With increasing respiratory event rate, the normalised high-frequency band power (HF Conclusion: The short-term HRV response differs based on the desaturation severity and the respiratory event rate in patients with suspected OSA. Therefore, a more detailed analysis of HRV and desaturation characteristics could enhance OSA severity estimation.

Identifiers

PMID36299363
PMCPMC9589326

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.