Evidence map›Paper›PMID 36299362›Full record

ArticleERJ open research2022

Infant lung function: criteria for selecting tidal flow-volume loops.

Karen Eline Stensby Bains, Hrefna Katrín Gudmundsdóttir, Martin Färdig, Erik Amnö, Christine M Jonassen, Björn Nordlund, Eva Maria Rehbinder, Håvard O Skjerven, Corina Silvia Rueegg, Riyas Vettukattil and 1 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Karen Eline Stensby BainsUniversity of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
Hrefna Katrín GudmundsdóttirUniversity of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
Martin FärdigAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Erik AmnöAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Christine M JonassenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Björn NordlundAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-9888-1659
Eva Maria RehbinderUniversity of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.ORCID https://orcid.org/0000-0002-1796-0433
Håvard O SkjervenUniversity of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.ORCID https://orcid.org/0000-0003-0168-2616
Corina Silvia RueeggOslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway.
Riyas VettukattilUniversity of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
Karin C Lødrup CarlsenUniversity of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
Oslo University Hospital · NOKarolinska University Hospital · SEØstfold Hospital Trust · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tidal flow-volume (TFV) loops are commonly recorded in infants during sleep, due to the more regular breathing patterns compared to the awake state. Standardised deselection of loops outside pre-specified ranges are based on periods of regular breathing, while criteria and available software for visual evaluation of TFV loops are lacking. We aimed to determine the reliability of standardised criteria for manual selection of infant TFV loops. Methods: Using a pre-defined set of criteria, three independent raters manually evaluated TFV loops among 57 randomly selected awake healthy 3-month-old infants with available TFV measurements in the Scandinavian Preventing Atopic Dermatitis and ALLergies in children (PreventADALL) study. The TFV loops were sampled using the Eco Medics Exhalyzer D. Criteria for selecting TFV loops included reproducible shape and volume with only one peak in tidal expiratory flow (PTEF), excluding loops with no clear or uneven flow towards PTEF. By intraclass coefficient (ICC), the reliability of agreement between raters was determined for the time to PTEF ( Results: Five infants had unsuccessful tests. Among the remaining 52 infants, the raters selected a median of 25, 26 and 15 loops per test. The ICCs (95% CI) were 0.97 (0.92-0.98) for Conclusion: Manual TFV loop selection using standardised criteria provides a reliable alternative for lung function measures in awake infants with interrupted breathing cycles in a real-life setting.

Identifiers

PMID36299362
PMCPMC9589321
OpenAlexW4296041660

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.