Evidence map›Paper›PMID 36299359›Full record

ArticleERJ open research2022

Neighbourhood disadvantage impacts on pulmonary function in patients with sarcoidosis.

Gillian C Goobie, Christopher J Ryerson, Kerri A Johannson, Spencer Keil, Erin Schikowski, Nasreen Khalil, Veronica Marcoux, Deborah Assayag, Hélène Manganas, Jolene H Fisher and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Association of Area Deprivation Index with Adherence to Proposed Regimen in Patients with Sarcoidosis in Detroit, Michigan.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 2 countries.

Gillian C GoobieDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0001-7982-5635
Christopher J RyersonDivision of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Kerri A JohannsonDivision of Respiratory Medicine, Department of Medicine, University of Calgary, Calgary, AB, Canada.ORCID https://orcid.org/0000-0003-1205-5511
Spencer KeilDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Erin SchikowskiDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Nasreen KhalilDivision of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Veronica MarcouxDivision of Respirology, Critical Care and Sleep Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Deborah AssayagDivision of Respiratory Medicine, Department of Medicine, McGill University, Montreal, QC, Canada.
Hélène ManganasDépartement de Médecine, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Jolene H FisherDivision of Respirology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Martin R J KolbDepartment of Medicine, Firestone Institute for Respiratory Health, The Research Institute of St Joe's Hamilton, St Joseph's Healthcare, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0003-3837-1467
Xiaoping ChenSimmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Kevin F GibsonSimmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Daniel J KassSimmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0001-6597-7830
Yingze ZhangDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0001-6947-2901
Kathleen O LindellSimmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
S Mehdi NouraieDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USUniversity of British Columbia · CACentre Hospitalier de l’Université de Montréal · CAMcGill University · CAMedical University of South Carolina · USSt. Joseph’s Healthcare Hamilton · CAUniversity of Calgary · CAUniversity of Saskatchewan · CAUniversity of Toronto · CA

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Translational studies for identifying and targeting novel pathways in systemic sclerosis pathogenesisP50AR060780 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAFYATIS, ROBERT A. · 2011 to 2021
$14.9M
Autoantibody-Targeted Therapy for Acute Exacerbations of Idiopathic Pulmonary FibrosisU01HL133232 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CRINER, GERARD J, DUNCAN, STEVEN R · 2017 to 2021
$3.8M
Pittsburgh Innovation in Collaborative Training of Residents AllianceR38HL150207 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Charles S Dela Cruz, Corrine R Kliment · 2020 to 2026
$2.1M
A novel approach to reverse the ineffectiveness of relaxin-based anti-fibrotic therapy in SScR21AR076024 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZHANG, YINGZE · 2019 to 2020
$379k
NCATS NIH HHS UL1 TR001857NHLBI NIH HHS R38 HL150207NHLBI NIH HHS U01 HL133232NIAMS NIH HHS P50 AR060780NIAMS NIH HHS R21 AR076024
6 · The paper itself

Abstract

Background: This multicentre, international, prospective cohort study evaluated whether patients with pulmonary sarcoidosis living in neighbourhoods with greater material and social disadvantage experience worse clinical outcomes. Methods: The area deprivation index and the Canadian Index of Multiple Deprivation evaluate neighbourhood-level disadvantage in the US and Canada, with higher scores reflecting greater disadvantage. Multivariable linear regression evaluated associations of disadvantage with baseline forced vital capacity (FVC) or diffusing capacity of the lung for carbon monoxide ( Results: We included 477 US and 122 Canadian patients with sarcoidosis. Higher disadvantage was not associated with survival or baseline FVC. The highest disadvantage quartile was associated with lower baseline Conclusion: Patients with sarcoidosis living in high disadvantage neighbourhoods experience worse baseline lung function and more rapid lung function decline, highlighting the need for better understanding of how neighbourhood-level factors impact individual patient outcomes.

Identifiers

PMID36299359
PMCPMC9589334
OpenAlexW4304974914

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.