ArticleMagnetic resonance in medicine2023
Building a tissue-unbiased brain template of fiber orientation distribution and tractography with multimodal registration.
Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 15 citations in OpenAlex.
- Streamline-Based Analysis: A novel framework for tractogram-driven streamline-wise statistical inference.Research square · 2026Article
- White matter pathways mediating dorsolateral prefrontal TMS therapy for depression.Nature neuroscience · 2026Article
- White matter changes in reward circuits of amyotrophic lateral sclerosis: a fixel-based study of appetite loss.BMC medicine · 2026Article
- Disentangling structure-function relationships between the human hippocampus and the whole brain using track-weighted dynamic functional connectivity.bioRxiv : the preprint server for biology · 2025Article
- Atlas-based templates vs. subject-specific tractography: resolving the debate.Brain structure & function · 2025Review
- Quantifying neurodegeneration within subdivisions of core motor pathways in amyotrophic lateral sclerosis using diffusion MRI.Journal of neurology · 2025Article
- Tractography from T1-weighted MRI: Empirically exploring the clinical viability of streamline propagation without diffusion MRI.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Internally consistent and fully unbiased multimodal MRI brain template construction from UK Biobank: Oxford-MM.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- A population-averaged structural connectomic brain atlas dataset from 422 HCP-aging subjects.Data in brief · 2023Article
- Convolutional-recurrent neural networks approximate diffusion tractography from T1-weighted MRI and associated anatomical context.bioRxiv : the preprint server for biology · 2023Article
- Building a tissue-unbiased brain template of fiber orientation distribution and tractography with multimodal registration.Magnetic resonance in medicine · 2023Article
- Editorial: Current advances in multimodal human brain imaging and analysis across the lifespan: From mapping to state prediction.Frontiers in neuroscience · 2023Article
- New insights into anatomical connectivity along the anterior-posterior axis of the human hippocampus usingeLife · 2022Article
- Structural connections between the noradrenergic and cholinergic system shape the dynamics of functional brain networks.NeuroImage · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeBrain templates provide an essential standard space for statistical analysis of brain structure and function. Despite recent advances, diffusion MRI still lacks a template of fiber orientation distribution (FOD) and tractography that is unbiased for both white and gray matter. Therefore, we aim to build up a set of such templates for better white-matter analysis and joint structural and functional analysis.
methodsWe have developed a multimodal registration method to leverage the complementary information captured by T
resultsOur FOD template preserves fine structural details in white matter and also, importantly, clear folding patterns in the cortex and good contrast in the subcortex. Quantitatively, our templates show better individual-template agreement at the whole-brain scale and segmentation scale. The tractography template aligns well with the gray matter, which led to fiber-centered functional connectivity showing high cross-group consistency.
conclusionWe have proposed a novel methodology for building a tissue-unbiased FOD and anatomically constrained tractography template based on multimodal registration. Our templates provide a standard space and statistical platform for not only white-matter analysis but also joint structural and functional analysis, therefore filling an important gap in multimodal neuroimage analysis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.