Evidence map›Paper›PMID 36298869›Full record

ArticleViruses2022

Impact of Early Pandemic SARS-CoV-2 Lineages Replacement with the Variant of Concern P.1 (Gamma) in Western Bahia, Brazil.

Josilene R Pinheiro, Esther C Dos Reis, Jéssica P Farias, Mayanna M C Fogaça, Patrícia de S da Silva, Itana Vivian R Santana, Ana Luiza S Rocha, Paloma O Vidal, Rafael da C Simões, Wilson B Luiz and 10 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Josilene R PinheiroCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.
Esther C Dos ReisCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.
Jéssica P FariasCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.
Mayanna M C FogaçaCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.
Patrícia de S da SilvaCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.
Itana Vivian R SantanaCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.
Ana Luiza S RochaCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.
Paloma O VidalCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.
Rafael da C SimõesCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.
Wilson B LuizDepartment of Biological Sciences, State University of Santa Cruz, Ilhéus 45662, BA, Brazil.
Alexander BirbrairDepartment of Dermatology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0003-1015-2561
Renato S de AguiarDepartment of Genetics, Ecology and Evolution, Federal University of Minas Gerais, Belo Horizonte 31270, MG, Brazil.ORCID 0000-0001-5180-3717
Renan P de SouzaDepartment of Genetics, Ecology and Evolution, Federal University of Minas Gerais, Belo Horizonte 31270, MG, Brazil.ORCID 0000-0002-9479-4432
Vasco A de C AzevedoDepartment of Genetics, Ecology and Evolution, Federal University of Minas Gerais, Belo Horizonte 31270, MG, Brazil.ORCID 0000-0002-4775-2280
Gepoliano ChavesDepartment of Pediatrics, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-8911-0542
Aline BelmokLaboratory of Baculoviruses, University of Brasilia, Brasilia 70910, DF, Brazil.
Ricardo Durães-CarvalhoDepartment of Microbiology, Immunology and Parasitology, São Paulo School of Medicine, Federal University of São Paulo (UNIFESP), São Paulo 04023, SP, Brazil.ORCID 0000-0001-5734-7601
Fernando L MeloLaboratory of Baculoviruses, University of Brasilia, Brasilia 70910, DF, Brazil.ORCID 0000-0002-9591-0239
Bergmann M RibeiroLaboratory of Baculoviruses, University of Brasilia, Brasilia 70910, DF, Brazil.
Jaime Henrique AmorimCenter of Biological Sciences and Health, Federal University of Western Bahia, Barreiras 47805, BA, Brazil.ORCID 0000-0002-0623-2879
Universidade Federal do Oeste da Bahia · BRUniversidade Federal de Minas Gerais · BRUniversidade de Brasília · BRUniversidade Estadual de Santa Cruz · BRUniversidade Federal de São Paulo · BRUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe correct understanding of the epidemiological dynamics of COVID-19, caused by the SARS-CoV-2, is essential for formulating public policies of disease containment.

methodsIn this study, we constructed a picture of the epidemiological dynamics of COVID-19 in a Brazilian population of almost 17000 patients in 15 months. We specifically studied the fluctuations of COVID-19 cases and deaths due to COVID-19 over time according to host gender, age, viral load, and genetic variants.

resultsAs the main results, we observed that the numbers of COVID-19 cases and deaths due to COVID-19 fluctuated over time and that men were the most affected by deaths, as well as those of 60 or more years old. We also observed that individuals between 30- and 44-years old were the most affected by COVID-19 cases. In addition, the viral loads in the patients' nasopharynx were higher in the early symptomatic period. We found that early pandemic SARS-CoV-2 lineages were replaced by the variant of concern (VOC) P.1 (Gamma) in the second half of the study period, which led to a significant increase in the number of deaths.

conclusionsThe results presented in this study are helpful for future formulations of efficient public policies of COVID-19 containment.

Indexed as

COVID-19SARS-CoV-2AdultBrazilHumansMaleMiddle AgedNasopharynxPandemicsCOVID-19impactvariant of concern

Identifiers

PMID36298869
PMCPMC9611628
OpenAlexW4307187984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.