Evidence map›Paper›PMID 36298856›Full record

ReviewViruses2022

Two Years of Genomic Surveillance in Belgium during the SARS-CoV-2 Pandemic to Attain Country-Wide Coverage and Monitor the Introduction and Spread of Emerging Variants.

Lize Cuypers, Simon Dellicour, Samuel L Hong, Barney I Potter, Bruno Verhasselt, Nick Vereecke, Laurens Lambrechts, Keith Durkin, Vincent Bours, Sofieke Klamer and 24 more

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 20 institutions in 1 country.

Lize CuypersNational Reference Centre for Respiratory Pathogens, Department of Laboratory Medicine, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-9433-8752
Simon DellicourSpatial Epidemiology Lab (SpELL), Université Libre de Bruxelles, 1000 Brussels, Belgium.ORCID 0000-0001-9558-1052
Samuel L HongDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-6354-4943
Barney I PotterDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3000 Leuven, Belgium.
Bruno VerhasseltDepartment of Diagnostic Sciences, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.
Nick VereeckePathoSense BV, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium.ORCID 0000-0001-5367-9756
Laurens LambrechtsHIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-1415-4591
Keith DurkinLaboratory of Human Genetics, GIGA Research Institute, 4000 Liège, Belgium.
Vincent BoursLaboratory of Human Genetics, GIGA Research Institute, 4000 Liège, Belgium.
Sofieke KlamerScientific Directorate of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium.
Guillaume Bayon-VicenteDepartment of Proteomic and Microbiology, Research Institute for Biosciences, University of Mons, 7000 Mons, Belgium.
Carl VaelClinical Laboratory, AZ Klina, 2930 Brasschaat, Belgium.
Kevin K AriënVirology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp, 2000 Antwerp, Belgium.ORCID 0000-0002-1340-4165
Ricardo De MendoncaDepartment of Microbiology, CUB-Hôpital Erasme, Université Libre de Bruxelles, 1000 Brussels, Belgium.
Oriane SoetensDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, 1090 Brussels, Belgium.ORCID 0000-0002-4281-9749
Charlotte MichelDepartment of Microbiology, Laboratoire Hospitalier Universitaire de Bruxelles (LHUB-ULB), 1000 Brussels, Belgium.
Bertrand BearzattoCenter for Applied Molecular Technologies (CTMA), Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain (UCLouvain), 1000 Brussels, Belgium.ORCID 0000-0001-5193-6819
Reinout NaesensDepartment of Medical Microbiology, Ziekenhuis Netwerk Antwerpen, 2020 Antwerp, Belgium.ORCID 0000-0003-1004-7737
Jeremie GrasInstitute of Pathology and Genetics (IPG), 6041 Gosselies, Belgium.
Anne VankeerberghenLaboratory of Molecular Biology, Campus Aalst-Asse-Ninove, Onze-Lieve-Vrouwziekenhuis, 9300 Aalst, Belgium.
Veerle MatheeussenLaboratory of Medical Microbiology, Department of Microbiology, Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, 2610 Wilrijk, Belgium.ORCID 0000-0003-2137-2068
Geert MartensDepartment of Laboratory Medicine, AZ Delta General Hospital, 8800 Roeselare, Belgium.
Dagmar ObbelsClinical Laboratory, Imelda Hospital, 2820 Bonheiden, Belgium.
Ann LemmensLaboratory of Clinical Biology, AZ Sint-Maarten Hospital, 2800 Mechelen, Belgium.
Bea Van den PoelClinical Laboratory, General Hospital Jan Portaels, 1800 Vilvoorde, Belgium.
Ellen Van EvenClinical Laboratory of Microbiology, HH Hospital Lier, 2500 Lier, Belgium.
Klara De RauwLaboratory of Clinical Biology, AZ Sint Lucas Hospital, 9000 Ghent, Belgium.
Luc WaumansClinical Laboratory, Jessa Hospital, 3500 Hasselt, Belgium.
Marijke ReyndersDepartment of Laboratory Medicine, Medical Microbiology, AZ Sint-Jan Bruges-Ostend AV, 8000 Bruges, Belgium.ORCID 0000-0003-2079-1279
Jonathan DegosserieFederal Testing Platform COVID-19, Department of Laboratory Medicine, CHU UCL Namur, 5530 Yvoir, Belgium.ORCID 0000-0001-8654-4831
COVID-19 Genomics Belgium Consortium
Piet MaesDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3000 Leuven, Belgium.
Emmanuel AndréNational Reference Centre for Respiratory Pathogens, Department of Laboratory Medicine, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-8321-3770
Guy BaeleDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-1915-7732
Rega Institute for Medical Research · BEAZ Sint-Jan · BEAZ Sint-Lucas · BEGhent University Hospital · BEKU Leuven · BEUniversité Libre de Bruxelles · BEUniversity of Antwerp · BEAZ Delta · BEAZ Klina · BECHU Dinant Godinne UCL Namur · BEGhent University · BEImelda Hospital · BEInstitute of Pathology and Genetics · BEJessa Hospital · BEOnze Lieve Vrouwziekenhuis Hospital · BESciensano (Belgium) · BEUCLouvain · BEUniversity of Liège · BEUniversity of Mons · BEVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An adequate SARS-CoV-2 genomic surveillance strategy has proven to be essential for countries to obtain a thorough understanding of the variants and lineages being imported and successfully established within their borders. During 2020, genomic surveillance in Belgium was not structurally implemented but performed by individual research laboratories that had to acquire the necessary funds themselves to perform this important task. At the start of 2021, a nationwide genomic surveillance consortium was established in Belgium to markedly increase the country's genomic sequencing efforts (both in terms of intensity and representativeness), to perform quality control among participating laboratories, and to enable coordination and collaboration of research projects and publications. We here discuss the genomic surveillance efforts in Belgium before and after the establishment of its genomic sequencing consortium, provide an overview of the specifics of the consortium, and explore more details regarding the scientific studies that have been published as a result of the increased number of Belgian SARS-CoV-2 genomes that have become available.

Indexed as

COVID-19PandemicsBelgiumGenome, ViralGenomicsHigh-Throughput Nucleotide SequencingHumansSARS-CoV-2BelgiumCOVID-19genomic surveillancenext-generation sequencingSARS-CoV-2variants of concern

Identifiers

PMID36298856
PMCPMC9612291
OpenAlexW4306970967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.