Evidence map›Paper›PMID 36298836›Full record

ArticleViruses2022

Serological Evidence of Severe Fever with Thrombocytopenia Syndrome Virus and IgM Positivity Were Identified in Healthy Residents in Vietnam.

Xuan Chuong Tran, Sung Hye Kim, Jeong-Eun Lee, So-Hee Kim, Su Yeon Kang, Nguyen D Binh, Pham V Duc, Phan T K Phuong, Nguyen T P Thao, Wonwoo Lee and 10 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

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  9. Epidemiological Characteristics of Severe Fever with Thrombocytopenia Syndrome.The American journal of tropical medicine and hygiene · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Xuan Chuong TranDepartment of Infectious Diseases, Hue University of Medicine and Pharmacy, Hue 530000, Vietnam.
Sung Hye KimDepartment of Microbiology and Environmental Biology & Medical Parasitology, Hanyang University College of Medicine, Seoul 04763, Korea.
Jeong-Eun LeeDepartment of Microbiology, Korea University College of Medicine, Seoul 02841, Korea.
So-Hee KimDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul 03080, Korea.
Su Yeon KangDepartment of Microbiology and Environmental Biology & Medical Parasitology, Hanyang University College of Medicine, Seoul 04763, Korea.ORCID 0000-0001-8776-2638
Nguyen D BinhDepartment of Infectious Diseases, Hue University of Medicine and Pharmacy, Hue 530000, Vietnam.
Pham V DucDepartment of Infectious Diseases, Hue University of Medicine and Pharmacy, Hue 530000, Vietnam.
Phan T K PhuongDepartment of Infectious Diseases, Hue University of Medicine and Pharmacy, Hue 530000, Vietnam.
Nguyen T P ThaoDepartment of Infectious Diseases, Hue University of Medicine and Pharmacy, Hue 530000, Vietnam.
Wonwoo LeeDepartment of Microbiology and Environmental Biology & Medical Parasitology, Hanyang University College of Medicine, Seoul 04763, Korea.
Joon-Yong BaeDepartment of Microbiology, Korea University College of Medicine, Seoul 02841, Korea.
Man-Seong ParkDepartment of Microbiology, Korea University College of Medicine, Seoul 02841, Korea.
Misun KimDepartment of Internal Medicine, Jeju National University College of Medicine, Jeju 64231, Korea.ORCID 0000-0003-3771-6101
Jeong Rae YooDepartment of Internal Medicine, Jeju National University College of Medicine, Jeju 64231, Korea.ORCID 0000-0002-5488-7925
Sang Taek HeoDepartment of Internal Medicine, Jeju National University College of Medicine, Jeju 64231, Korea.ORCID 0000-0001-8947-5069
Kyeong Ho AnDepartment of Microbiology, Graduate School of Dongguk University, Seoul 04620, Korea.
Jung Mogg KimDepartment of Microbiology and Environmental Biology & Medical Parasitology, Hanyang University College of Medicine, Seoul 04763, Korea.ORCID 0000-0002-6506-7519
Nam-Hyuk ChoDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0003-3673-6397
Sun-Ho KeeDepartment of Microbiology, Korea University College of Medicine, Seoul 02841, Korea.
Keun Hwa LeeDepartment of Microbiology and Environmental Biology & Medical Parasitology, Hanyang University College of Medicine, Seoul 04763, Korea.ORCID 0000-0001-9600-461X
Hue University · VNHanyang University · KRKorea University · KRJeju National University · KRSeoul National University · KRDongguk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe fever with thrombocytopenia syndrome (SFTS), an emerging tick-borne viral disease, is prevalent in East Asia and has also been reported in Southeast Asia since 2019. SFTS patients in Vietnam were first reported in 2019. However, the seroprevalence of severe fever with thrombocytopenia syndrome virus (SFTSV) in Vietnam has not been reported. To investigate the seroprevalence of SFTSV in Vietnam, we collected serum samples from 714 healthy residents in Thua Thien Hue and Quang Nam Province, Vietnam, and the seroprevalence of SFTSV was assessed using immunofluorescence antibody assay (IFA), Enzyme-Linked Immunosorbent Assays (ELISAs) and the 50% focus reduction neutralization test (FRNT50) assay. The seroprevalence of anti-SFTSV IgM or IgG was observed to be 3.64% (26/714), high IgM positivity was >80 (0.28%, 2/714) and the titer of neutralizing antibodies against SFTSV ranged from 15.5 to 55.9. In Pakistan, SFTSV infection confirmed using a microneutralization test (MNT) assay (prevalence is 2.5%) and ELISAs showed a high seroprevalence (46.7%) of SFTSV. Hence, the seroprevalence rate in Vietnam is similar to that in Pakistan and the number of SFTS patients could increase in Vietnam.

Indexed as

Bunyaviridae InfectionsPhlebovirusSevere Fever with Thrombocytopenia SyndromeTick-Borne DiseasesAntibodies, NeutralizingAntibodies, ViralHumansImmunoglobulin GImmunoglobulin MSeroepidemiologic StudiesVietnamAntibodies, NeutralizingAntibodies, ViralImmunoglobulin GImmunoglobulin Mhealthy residentsIgM positivityserological evidencesevere fever with thrombocytopenia syndrome virus (SFTSV)Vietnam

Identifiers

PMID36298836
PMCPMC9607213
OpenAlexW4306673411

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.