Evidence map›Paper›PMID 36298774›Full record

ArticleViruses2022

Macrophage Migration Inhibitory Factor (MIF) Promotes Increased Proportions of the Highly Permissive Th17-like Cell Profile during HIV Infection.

César Trifone, Lucía Baquero, Alejandro Czernikier, Paula Benencio, Lin Leng, Natalia Laufer, María Florencia Quiroga, Richard Bucala, Yanina Ghiglione, Gabriela Turk

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

César TrifoneFacultad de Medicina, Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina.
Lucía BaqueroInstituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), CONICET-Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina.
Alejandro CzernikierFacultad de Medicina, Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina.
Paula BenencioFacultad de Medicina, Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina.ORCID 0000-0001-6471-748X
Lin LengDepartment of Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.ORCID 0000-0002-0605-358X
Natalia LauferInstituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), CONICET-Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina.
María Florencia QuirogaInstituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), CONICET-Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina.ORCID 0000-0002-0956-5492
Richard BucalaDepartment of Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.
Yanina GhiglioneFacultad de Medicina, Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina.
Gabriela TurkInstituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), CONICET-Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina.ORCID 0000-0002-4808-670X
Consejo Nacional de Investigaciones Científicas y Técnicas · ARYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

In this study, we evaluate the role of the MIF/CD74 axis in the functionality of CD4

Indexed as

HIV InfectionsMacrophage Migration-Inhibitory FactorsTh17 CellsAntigens, Differentiation, B-LymphocyteCellular MicroenvironmentHistocompatibility Antigens Class IIHumansInterleukin-17Interleukin-6Interleukin-8Intramolecular OxidoreductasesNuclear Receptor Subfamily 1, Group F, Member 3Transcription FactorsAntigens, Differentiation, B-LymphocyteHistocompatibility Antigens Class IIInterleukin-17Interleukin-6Interleukin-8Intramolecular Oxidoreductasesinvariant chainMacrophage Migration-Inhibitory FactorsMIF protein, humanNuclear Receptor Subfamily 1, Group F, Member 3Transcription FactorsHIVimmune pathogenesisMDM/CD4TL co-cultureMIF

Identifiers

PMID36298774
PMCPMC9611675
OpenAlexW4304811512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.