Evidence map›Paper›PMID 36298710›Full record

ReviewViruses2022

Monkeypox: A Comprehensive Review.

Harapan Harapan, Youdiil Ophinni, Dewi Megawati, Andri Frediansyah, Sukamto S Mamada, Mirnawati Salampe, Talha Bin Emran, Wira Winardi, Raisha Fathima, Salin Sirinam and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Evaluation of a Novel Multiplex PCR Assay for Vesicular Viruses.International journal of molecular sciences · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Marburg Virus Disease: A Narrative Review.Health science reports · 2025
    Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 8 countries.

Harapan HarapanMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.ORCID 0000-0001-7630-8413
Youdiil OphinniRagon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Dewi MegawatiDepartment of Veterinary Pathobiology, School of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0001-9230-2265
Andri FrediansyahResearch Group for Food Microbiology and Biotechnology, National Research and Innovation Agency (BRIN), Yogyakarta 55861, Indonesia.ORCID 0000-0003-4923-2948
Sukamto S MamadaDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia.
Mirnawati SalampeSekolah Tinggi Ilmu Farmasi Makassar, Makassar 90242, Indonesia.
Talha Bin EmranDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.ORCID 0000-0003-3188-2272
Wira WinardiDepartment of Pulmonology and Respiratory Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.ORCID 0000-0002-0880-7445
Raisha FathimaMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.
Salin SirinamDepartment of Tropical Pediatrics, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.ORCID 0000-0001-8254-7066
Pichamon SittikulDepartment of Tropical Pediatrics, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Ana M StoianDepartment of Medical Microbiology and Immunology, School of Medicine, University of California Davis, Davis, CA 95616, USA.
Firzan NainuDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia.ORCID 0000-0003-0989-4023
Malik SallamDepartment of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman 11942, Jordan.ORCID 0000-0002-0165-9670
Universitas Syiah Kuala · IDHasanuddin University · IDMahidol University · THDaffodil International University · BDMissouri College · USNational Agricultural Research and Innovation Centre · HURagon Institute of MGH, MIT and Harvard · USUniversitas Patria Artha · IDUniversity of California, Davis · USUniversity of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2022 multi-country monkeypox outbreak in humans has brought new public health adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease has spread to 104 countries throughout six continents of the world, with the highest burden in North America and Europe. The etiologic agent, monkeypox virus (MPXV), has been known since 1959 after isolation from infected monkeys, and virulence among humans has been reported since the 1970s, mainly in endemic countries in West and Central Africa. However, the disease has re-emerged in 2022 at an unprecedented pace, with particular concern on its human-to-human transmissibility and community spread in non-endemic regions. As a mitigation effort, healthcare workers, public health policymakers, and the general public worldwide need to be well-informed on this relatively neglected viral disease. Here, we provide a comprehensive and up-to-date overview of monkeypox, including the following aspects: epidemiology, etiology, pathogenesis, clinical features, diagnosis, and management. In addition, the current review discusses the preventive and control measures, the latest vaccine developments, and the future research areas in this re-emerging viral disease that was declared as a public health emergency of international concern.

Indexed as

COVID-19Mpox, MonkeypoxVaccinesDisease OutbreaksHumansMonkeypox virusVaccinesemergencyemerging viral infectious diseasesepidemicinternational concernpreventionpublic healthvaccinationzoonosis

Identifiers

PMID36298710
PMCPMC9612348
OpenAlexW4298110654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.