Evidence map›Paper›PMID 36298659›Full record

ArticleViruses2022

Design of Three Residues Peptides against SARS-CoV-2 Infection.

Carla Zannella, Annalisa Chianese, Giuseppe Greco, Biagio Santella, Giuseppe Squillaci, Alessandra Monti, Nunzianna Doti, Giuseppina Sanna, Aldo Manzin, Alessandra Morana and 5 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Identification of Z-Tyr-Ala-CHNMicroorganisms · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Carla ZannellaDepartment of Experimental Medicine, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0001-7991-8700
Annalisa ChianeseDepartment of Experimental Medicine, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-1648-4519
Giuseppe GrecoDepartment of Experimental Medicine, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.
Biagio SantellaDepartment of Experimental Medicine, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-5010-1390
Giuseppe SquillaciResearch Institute on Terrestrial Ecosystems, National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-9310-3564
Alessandra MontiInstitute of Biostructures and Bioimaging (IBB), National Research Council (CNR), 80134 Naples, Italy.
Nunzianna DotiInstitute of Biostructures and Bioimaging (IBB), National Research Council (CNR), 80134 Naples, Italy.
Giuseppina SannaDepartment of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, 09042 Cagliari, Italy.ORCID 0000-0002-3999-4263
Aldo ManzinDepartment of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, 09042 Cagliari, Italy.ORCID 0000-0003-2961-3428
Alessandra MoranaResearch Institute on Terrestrial Ecosystems, National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy.ORCID 0000-0003-3189-2526
Anna De FilippisDepartment of Experimental Medicine, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-0395-7962
Gianni D'AngeloDepartment of Computer Science, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, Italy.ORCID 0000-0001-7164-5736
Francesco PalmieriDepartment of Computer Science, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, Italy.
Gianluigi FranciDepartment of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0003-3321-4331
Massimiliano GaldieroDepartment of Experimental Medicine, Università degli Studi della Campania Luigi Vanvitelli, 80138 Naples, Italy.ORCID 0000-0002-1576-6290
University of Campania "Luigi Vanvitelli" · ITUniversity of Salerno · ITInstitute of Biostructure and Bioimaging · ITNational Research Council · ITUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The continuous and rapid spread of the COVID-19 pandemic has emphasized the need to seek new therapeutic and prophylactic treatments. Peptide inhibitors are a valid alternative approach for the treatment of emerging viral infections, mainly due to their low toxicity and high efficiency. Recently, two small nucleotide signatures were identified in the genome of some members of the

Indexed as

COVID-19 Drug TreatmentAntiviral AgentsHumansMolecular Docking SimulationNucleotidesPandemicsPeptide HydrolasesPeptidesSARS-CoV-2Spike Glycoprotein, CoronavirusAntiviral AgentsNucleotidesPeptide HydrolasesPeptidesSpike Glycoprotein, Coronaviruscoronavirusdockingentry inhibitorspeptidesSARS-CoV-2spike protein

Identifiers

PMID36298659
PMCPMC9612326
OpenAlexW4296997411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.