Evidence map›Paper›PMID 36298601›Full record

ReviewVaccines2022

The Role of Reactive Species on Innate Immunity.

Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Celia Andrés Juan, Francisco J Plou, Eduardo Pérez-Lebeña

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 101 citations in OpenAlex.

  1. Article
  2. Review
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  8. Article
  9. Contradictory Effects on Hepatocytes in ASMD.International journal of molecular sciences · 2026
    Review
  10. Article
  11. Mature-StageInternational journal of molecular sciences · 2026
    Article
  12. The Oxidative Stress: Origin and Role in Aging and Diseases.Antioxidants (Basel, Switzerland) · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Review
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  18. Article
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  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Celia María Curieses AndrésHospital Clínico Universitario of Valladolid, Avenida de Ramón y Cajal 3, 47003 Valladolid, Spain.
José Manuel Pérez de la LastraInstitute of Natural Products and Agrobiology, CSIC-Spanish Research Council, Avda. Astrofísico Fco. Sánchez 3, 38206 La Laguna, Spain.ORCID 0000-0003-4663-5565
Celia Andrés JuanCinquima Institute and Department of Organic Chemistry, Faculty of Sciences, Valladolid University, Paseo de Belén 7, 47011 Valladolid, Spain.
Francisco J PlouInstitute of Catalysis and Petrochemistry, CSIC-Spanish Research Council, 28049 Madrid, Spain.ORCID 0000-0003-0831-893X
Eduardo Pérez-LebeñaSistemas de Biotecnología y Recursos Naturales, 47625 Valladolid, Spain.
Hospital Clínico Universitario de Valladolid · ESInstituto de Catálisis y Petroleoquímica · ESInstituto de Productos Naturales y Agrobiología · ESUniversidad de Valladolid · ES

Funding

Agencia Canaria de Investigación, Innovación y Sociedad de la Información project ProID2020010134Cooperation Program INTERREG-MAC 2014-2020, with European Funds for Regional De-velopment-FEDER APOGEOFundación CajaCanarias project 2019SP43Spanish Ministry of Economy and Competitiveness Grant PID2019-105838RB-C31
6 · The paper itself

Abstract

This review examines the role of reactive species RS (of oxygen ROS, nitrogen RNS and halogen RHS) on innate immunity. The importance of these species in innate immunity was first recognized in phagocytes that underwent a "respiratory burst" after activation. The anion superoxide

Indexed as

antimicrobialinnate immunityreactive speciesRNS and RHSROS

Identifiers

PMID36298601
PMCPMC9609844
OpenAlexW4306760805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.