Evidence map›Paper›PMID 36298577›Full record

ArticleVaccines2022

Cost-Effectiveness of COVID-19 Sequential Vaccination Strategies in Inactivated Vaccinated Individuals in China.

Yaqun Fu, Jingyu Zhao, Xia Wei, Peien Han, Li Yang, Tao Ren, Siyan Zhan, Liming Li

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yaqun FuSchool of Public Health, Peking University, Beijing 100191, China.ORCID 0000-0002-2606-477X
Jingyu ZhaoSchool of Public Health, Peking University, Beijing 100191, China.
Xia WeiLondon School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Peien HanSchool of Public Health, Peking University, Beijing 100191, China.
Li YangSchool of Public Health, Peking University, Beijing 100191, China.ORCID 0000-0003-0640-2003
Tao RenSchool of Public Health, Peking University, Beijing 100191, China.
Siyan ZhanSchool of Public Health, Peking University, Beijing 100191, China.ORCID 0000-0001-7252-5349
Liming LiSchool of Public Health, Peking University, Beijing 100191, China.
Peking University · CNUniversity of London · GB

Funding

Capital Health Research and Development of Special Fund [2021-1G-4091]National Natural Science Foundation of China [72174010]Natural Science Foundation of Beijing Municipality [M22033]
6 · The paper itself

Abstract

To effectively prevent and control the COVID-19 pandemic, countries have adopted a booster vaccination strategy. This study aimed to estimate the cost-effectiveness of sequential booster COVID-19 vaccination compared to two-dose inactivated vaccination in China from a societal perspective. A Markov model was developed to estimate the cost-effectiveness of sequential vaccination, including two doses of an inactivated vaccine followed by a booster shot of an inactivated vaccine, adenovirus vectored vaccine, protein subunit vaccine, or mRNA vaccine. The incremental effects of a booster shot with an inactivated vaccine, protein subunit vaccine, adenovirus vectored vaccine, and mRNA vaccine were 0.0075, 0.0110, 0.0208, and 0.0249 QALYs and saved costs of US$163.96, US$261.73, US$583.21, and US$724.49, respectively. Under the Omicron virus pandemic, the sequential vaccination among adults and the elderly (aged 60-69, 70-79, over 80) was consistently cost-saving, and a booster shot of the mRNA vaccine was more cost-saving. The results indicate that the sequential vaccination strategy is cost-effective in addressing the COVID-19 pandemic, and improving vaccination coverage among the elderly is of great importance in avoiding severe cases and deaths.

Indexed as

boostercost-effectivenessCOVID-19Markov modelsequential vaccination

Identifiers

PMID36298577
PMCPMC9610874
OpenAlexW4306404277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.