Evidence map›Paper›PMID 36298557›Full record

ArticleVaccines2022

Recurrent and De Novo Toxoplasmosis Retinochoroiditis following Coronavirus Disease 2019 Infection or Vaccination.

Mélanie Hébert, Soumaya Bouhout, Julie Vadboncoeur, Marie-Josée Aubin

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mélanie HébertDepartment of Ophthalmology, Université Laval, Quebec, QC G1V 0A6, Canada.ORCID 0000-0002-5738-4362
Soumaya BouhoutDepartment of Ophthalmology, Université de Montréal, Montreal, QC H3T 1J4, Canada.
Julie VadboncoeurDepartment of Ophthalmology, Université de Montréal, Montreal, QC H3T 1J4, Canada.
Marie-Josée AubinDepartment of Ophthalmology, Université de Montréal, Montreal, QC H3T 1J4, Canada.
Hôpital Maisonneuve-Rosemont · CAUniversité de Montréal · CAUniversité Laval · CA

Funding

Vice-Dean of Research and Development of the Université de Montréal Philanthropic fundsVision Health Research Network Common Infrastructures program
6 · The paper itself

Abstract

This study reports three cases of toxoplasmosis retinochoroiditis following coronavirus disease 2019 (COVID-19) infection or vaccination from the national Canadian COVID-19 Eye Registry between December 2020 and September 2021. A 56-year-old male presented 15 days after a positive COVID-19 test with toxoplasmosis retinochoroiditis. He later relapsed 8 days following a first Pfizer-BioNTech vaccine dose. Two patients presented with toxoplasmosis retinochoroiditis following COVID-19 vaccination: A 58-year-old female presenting 4 days following a first Pfizer-BioNTech vaccine dose with anterior uveitis and a posterior pole lesion discovered 3 months later and a 39-year-old female presenting 17 days after a first Moderna vaccine dose. Resolution was achieved with oral clindamycin, oral trimethoprim/sulfamethoxazole, and topical prednisolone acetate 1%. Patients were offered prophylactic trimethoprim/sulfamethoxazole for subsequent doses without relapse. Following COVID-19 infection or vaccination, patients may be at risk for toxoplasmosis retinochoroiditis. Prophylactic antibiotics for future doses may be offered to patients with known ocular toxoplasmosis to prevent recurrence.

Indexed as

antibiotic prophylaxiscoronavirus disease 2019COVID-19 vaccinationinflammationmRNA vaccineophthalmic adverse eventsSARS-CoV-2toxoplasmosis retinochoroiditisvaccination

Identifiers

PMID36298557
PMCPMC9609888
OpenAlexW4304189966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.