Evidence map›Paper›PMID 36298491›Full record

ReviewVaccines2022

A Vaccine for Canine Rocky Mountain Spotted Fever: An Unmet One Health Need.

David H Walker, Lucas S Blanton, Maureen Laroche, Rong Fang, Hema P Narra

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Infection and immunity · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Rocky Mountain Spotted Fever in Mexico: A Call to Action.The American journal of tropical medicine and hygiene · 2024
    Article
  9. Review
  10. Article
  11. Key molecules regulating the blood meals ofVeterinary research forum : an international quarterly journal · 2024
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David H WalkerDepartment of Pathology, The University of Texas Medical Branch at Galveston, 301 University Blvd., Galveston, TX 77555-0609, USA.ORCID 0000-0002-3309-4360
Lucas S BlantonDepartment of Internal Medicine, Division of Infectious Diseases, The University of Texas Medical Branch at Galveston, 301 University Blvd., Galveston, TX 77555-0435, USA.
Maureen LarocheDepartment of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, 301 University Blvd., Galveston, TX 77555-1019, USA.ORCID 0000-0002-5764-2421
Rong FangDepartment of Pathology, The University of Texas Medical Branch at Galveston, 301 University Blvd., Galveston, TX 77555-0609, USA.
Hema P NarraDepartment of Pathology, The University of Texas Medical Branch at Galveston, 301 University Blvd., Galveston, TX 77555-0609, USA.
The University of Texas Medical Branch at Galveston · US

Funding

Rational development of a vaccine against tick-borne rickettsiosesR01AI163857 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI FANG, RONG MEGAN · 2022 to 2025
$3.2M
Novel Bacterial Small RNAs as Determinants of Rickettsial Virulence and TransmissionR01AI127899 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI NARRA, HEMA PRASAD · 2018 to 2021
$2.1M
Mechanisms by which rickettsiae subvert autophagy pathway in macrophagesR21AI151904 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI FANG, RONG MEGAN · 2021 to 2022
$440k
Mechanisms by which rickettsiae increase microvascular permeabilityR21AI133359 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI FANG, RONG MEGAN · 2018 to 2019
$434k
NIAID NIH HHS R01 AI127899NIAID NIH HHS R01 AI163857NIAID NIH HHS R21 AI133359NIAID NIH HHS R21 AI151904
6 · The paper itself

Abstract

Outbreaks of life-threatening Rocky Mountain spotted fever in humans and dogs associated with a canine-tick maintenance cycle constitute an important One Health opportunity. The reality of the problem has been observed strikingly in Mexico, Brazil, Colombia, and Native American tribal lands in Arizona. The brown dog tick,

Indexed as

canine vector-borne diseaselive attenuated vaccineOne HealthRhipicephalus sanguineusRickettsia rickettsiiRocky Mountain spotted feversubunit vaccine

Identifiers

PMID36298491
PMCPMC9610744
OpenAlexW4298003297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.