Evidence map›Paper›PMID 36297986›Full record

ArticlePolymers2022

Characterization of the Interaction of Polymeric Micelles with siRNA: A Combined Experimental and Molecular Dynamics Study.

Franck Marquet, Filip Stojceski, Gianvito Grasso, Viorica Patrulea, Andrea Danani, Gerrit Borchard

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Franck MarquetSection of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel-Servet 1, 1211 Geneva, Switzerland.ORCID 0000-0002-0562-5099
Filip StojceskiDalle Molle Institute for Artificial Intelligence (IDSIA), University of Italian Switzerland (USI), University of Applied Science and Art of Southern Switzerland (SUPSI), Polo Universitario Lugano-Campus Est, Via la Santa 1, CH-6962 Lugano-Viganello, Switzerland.ORCID 0000-0001-8778-8395
Gianvito GrassoDalle Molle Institute for Artificial Intelligence (IDSIA), University of Italian Switzerland (USI), University of Applied Science and Art of Southern Switzerland (SUPSI), Polo Universitario Lugano-Campus Est, Via la Santa 1, CH-6962 Lugano-Viganello, Switzerland.
Viorica PatruleaSection of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel-Servet 1, 1211 Geneva, Switzerland.ORCID 0000-0003-3906-2041
Andrea DananiDalle Molle Institute for Artificial Intelligence (IDSIA), University of Italian Switzerland (USI), University of Applied Science and Art of Southern Switzerland (SUPSI), Polo Universitario Lugano-Campus Est, Via la Santa 1, CH-6962 Lugano-Viganello, Switzerland.ORCID 0000-0001-6578-5089
Gerrit BorchardSection of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel-Servet 1, 1211 Geneva, Switzerland.ORCID 0000-0001-6268-2586
University of Applied Sciences and Arts of Southern Switzerland · CHUniversity of Geneva · CH

Funding

Swiss National Science Foundation ID 200021_157033Swiss National Science Foundation ID P400PM_194482
6 · The paper itself

Abstract

The simulation of large molecular systems remains a daunting challenge, which justifies the exploration of novel methodologies to keep computers as an ideal companion tool for everyday laboratory work. Whole micelles, bigger than 20 nm in size, formed by the self-assembly of hundreds of copolymers containing more than 50 repeating units, have until now rarely been simulated, due to a lack of computational power. Therefore, a flexible amphiphilic triblock copolymer (mPEG

Indexed as

binding affinitycapillary zone electrophoresiscomplexation efficiencyisothermal titration calorimetrymolecular dynamicspolymeric micelles

Identifiers

PMID36297986
PMCPMC9611052
OpenAlexW4306847937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.