Evidence map›Paper›PMID 36297632›Full record

ArticlePharmaceutics2022

Gold-Polypyrrole-Loaded Eosin in Photo-Mediated Treatment of Hidradenitis Suppurativa: In Vivo Trans-Epidermal Permeation Study and Clinical Case Report.

Abdullah I El-Kholy, Maha Fadel, Maha Nasr, Ibrahim El-Sherbiny, Abeer Tawfik, Yasser O Mosaad, Doaa Abdel Fadeel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Abdullah I El-KholyDepartment of Medical Applications of Laser, Pharmaceutical Nano-Technology Unit, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza 12613, Egypt.
Maha FadelDepartment of Medical Applications of Laser, Pharmaceutical Nano-Technology Unit, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza 12613, Egypt.
Maha NasrDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.
Ibrahim El-SherbinyNanomaterials Lab, Center for Materials Science, Zewail City of Science and Technology, 6th October City, Giza 12578, Egypt.ORCID 0000-0002-8179-437X
Abeer TawfikDepartment of Medical Applications of Laser, Dermatology Unit, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza 12613, Egypt.
Yasser O MosaadDepartment of Pharmacy Practice and Clinical Pharmacy, Faculty of Pharmaceutical Sciences and Pharmaceutical Industries, Future University, Cairo 11835, Egypt.
Doaa Abdel FadeelDepartment of Medical Applications of Laser, Pharmaceutical Nano-Technology Unit, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza 12613, Egypt.ORCID 0000-0002-2998-0239
Cairo University · EGAin Shams University · EGFuture University in Egypt · EGZewail City of Science and Technology · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study reports a new protocol for the management of Hidradenitis Suppurativa (HS), depending on the synergistic photodynamic and photothermal effect of eosin yellow-gold-polypyrrole hybrid nanoparticles (E-G-Ppy NPs). E-G-Ppy NPs and gold-polypyrrole NPs (G-Ppy NPs) were synthesized, characterized, and formulated in topical hydrogels. Then, in vivo trans-epidermal permeation study, under both dark and white light-irradiation conditions, was done on albino mice. The E-G-Ppy hydrogel was then applied on a twenty-four years old female with recurrent axillary HS lesions pretreated with fractional CO

Indexed as

eosin yellowgoldHidradenitis Suppurativaphotodynamicphotothermalpolypyrrole

Identifiers

PMID36297632
PMCPMC9612129
OpenAlexW4306399609

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.