Evidence map›Paper›PMID 36297610›Full record

ArticlePharmaceutics2022

Novel pH-Responsive Cubosome and Hexosome Lipid Nanocarriers of SN-38 Are Prospective for Cancer Therapy.

Sarigama Rajesh, Jiali Zhai, Calum J Drummond, Nhiem Tran

Abstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Liquid crystalline system for drug delivery: structural insights, preparation techniques and translational potential.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
  2. Review
  3. Article
  4. Recent Developments in Nanoparticle-Hydrogel Hybrid Materials for Controlled Release.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarigama RajeshSchool of Science, STEM College, RMIT University, Melbourne, VIC 3000, Australia.
Jiali ZhaiSchool of Science, STEM College, RMIT University, Melbourne, VIC 3000, Australia.ORCID 0000-0002-9882-9014
Calum J DrummondSchool of Science, STEM College, RMIT University, Melbourne, VIC 3000, Australia.ORCID 0000-0001-7340-8611
Nhiem TranSchool of Science, STEM College, RMIT University, Melbourne, VIC 3000, Australia.ORCID 0000-0002-0209-2434

Funding

Maxwell Eagle Endowment Award N/ARMIT University N/A
6 · The paper itself

Abstract

pH-responsive nanoparticles enable the selective delivery of a chemotherapeutic agent to tumours while reducing adverse effects. Herein we synthesised four novel aminolipids and developed pH-responsive nanostructured lipid nanoparticles (LNP), which exhibited a slow-releasing hexagonal structure (H

Indexed as

aminolipidcubosomesdrug deliveryhexosomesionisable lipidslipid-nanoparticles (LNPs)lyotropic liquid crystalsMOpH-responsiveself-assemblySN-38

Identifiers

PMID36297610
PMCPMC9609773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.