Evidence map›Paper›PMID 36297601›Full record

ReviewPharmaceutics2022

Advances in

Sui Wai Ling, Erik de Blois, Eline Hooijman, Astrid van der Veldt, Tessa Brabander

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Assessment of the therapeutic efficacy of [European journal of nuclear medicine and molecular imaging · 2025
    Pooled it
  2. [International journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Challenges and Opportunities in Radioligand Therapy.Journal of nuclear medicine technology · 2025
    Review
  7. Review
  8. Framework to calculateMedical physics · 2025
    Article
  9. Review
  10. First real-world clinical experience with [European journal of nuclear medicine and molecular imaging · 2025
    Article
  11. JHU-2545 preferentially shields salivary glands and kidneys during PSMA-targeted imaging.European journal of nuclear medicine and molecular imaging · 2025
    Article
  12. Article
  13. Ac-225 radiochemistry through the lens of [EJNMMI radiopharmacy and chemistry · 2025
    Article
  14. Article
  15. Androgen Signaling in Prostate Cancer: When a Friend Turns Foe.Endocrine, metabolic & immune disorders drug targets · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sui Wai LingDepartment of Radiology & Nuclear Medicine, Erasmus MC, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-1084-631X
Erik de BloisDepartment of Radiology & Nuclear Medicine, Erasmus MC, 3015 GD Rotterdam, The Netherlands.
Eline HooijmanDepartment of Radiology & Nuclear Medicine, Erasmus MC, 3015 GD Rotterdam, The Netherlands.
Astrid van der VeldtDepartment of Radiology & Nuclear Medicine, Erasmus MC, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-0446-1907
Tessa BrabanderDepartment of Radiology & Nuclear Medicine, Erasmus MC, 3015 GD Rotterdam, The Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For patients with metastatic castration-resistant prostate cancer (mCRPC), the survival benefit of classic treatment options with chemotherapy and drugs targeting androgen signaling is limited. Therefore, beta and alpha radionuclide therapy (RNT) have emerged as novel treatment options for patients with mCRPC. Radioligands target the prostate-specific membrane antigen (PSMA) epitopes, which are upregulated up to a thousand times more in prostate cancer cells compared to the cells in normal tissues. For this reason, PSMA is an excellent target for both imaging and therapy. Over the past years, many studies have investigated the treatment effects of lutetium-177 labeled PSMA (

Indexed as

actinium-225lutetium-177metastatic castration-resistant prostate cancer (mCRPC)prostate-specific membrane antigen (PSMA)radionuclide therapy (RNT)

Identifiers

PMID36297601
PMCPMC9607057
OpenAlexW4304630351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.