Evidence map›Paper›PMID 36297486›Full record

ReviewPharmaceutics2022

Efficacy of Antimicrobial Photodynamic Therapy Mediated by Photosensitizers Conjugated with Inorganic Nanoparticles: Systematic Review and Meta-Analysis.

Túlio Morandin Ferrisse, Luana Mendonça Dias, Analú Barros de Oliveira, Cláudia Carolina Jordão, Ewerton Garcia de Oliveira Mima, Ana Claudia Pavarina

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Enhanced photodynamic disruption of multidrug-resistantBiochemistry and biophysics reports · 2025
    Article
  3. Cationic Bacteriochlorin in the photodynamic inactivation of microorganisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Article
  5. Recent Advances in the Application of Cucurbitacin B as an Anticancer Agent.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Túlio Morandin FerrisseDepartment of Dental Materials and Prosthodontics, School of Dentistry at Araraquara, Universidade Estadual Paulista (UNESP), Araraquara 14801-903, SP, Brazil.ORCID 0000-0002-9933-2819
Luana Mendonça DiasDepartment of Dental Materials and Prosthodontics, School of Dentistry at Araraquara, Universidade Estadual Paulista (UNESP), Araraquara 14801-903, SP, Brazil.
Analú Barros de OliveiraDepartment of Morphology, Pediatric Dentistry and Orthodontic, School of Dentistry, São Paulo State University (UNESP), Araraquara 14801-903, SP, Brazil.
Cláudia Carolina JordãoDepartment of Dental Materials and Prosthodontics, School of Dentistry at Araraquara, Universidade Estadual Paulista (UNESP), Araraquara 14801-903, SP, Brazil.
Ewerton Garcia de Oliveira MimaDepartment of Dental Materials and Prosthodontics, School of Dentistry at Araraquara, Universidade Estadual Paulista (UNESP), Araraquara 14801-903, SP, Brazil.ORCID 0000-0002-9575-7625
Ana Claudia PavarinaDepartment of Dental Materials and Prosthodontics, School of Dentistry at Araraquara, Universidade Estadual Paulista (UNESP), Araraquara 14801-903, SP, Brazil.ORCID 0000-0002-9231-1994

Funding

São Paulo Research Foundation 2013/07276-1São Paulo Research Foundation 2019/27634-6São Paulo Research Foundation 2020/07110-0São Paulo Research Foundation 2020/16227-8São Paulo Research Foundation 2021/01191-0
6 · The paper itself

Abstract

Antimicrobial photodynamic therapy (aPDT) is a method that does not seem to promote antimicrobial resistance. Photosensitizers (PS) conjugated with inorganic nanoparticles for the drug-delivery system have the purpose of enhancing the efficacy of aPDT. The present study was to perform a systematic review and meta-analysis of the efficacy of aPDT mediated by PS conjugated with inorganic nanoparticles. The PubMed, Scopus, Web of Science, Science Direct, Cochrane Library, SciELO, and Lilacs databases were searched. OHAT Rob toll was used to assess the risk of bias. A random effect model with an odds ratio (OR) and effect measure was used. Fourteen articles were able to be included in the present review. The most frequent microorganisms evaluated were

Indexed as

antimicrobial photodynamic therapydrug-delivery systemEscherichia coliinorganic nanoparticlesmeta-analysisStaphylococcus aureussystematic review

Identifiers

PMID36297486
PMCPMC9612113

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.