Evidence map›Paper›PMID 36297448›Full record

ArticlePharmaceutics2022

In Vitro and In Vivo Relevant Antineoplastic Activity of Platinum(II) Complexes toward Triple-Negative MDA-MB-231 Breast Cancer Cell Line.

Leide Laura Figueiredo Maciel, Marina Barreto Silva, Rafaela Oliveira Moreira, Ana Paula Cardoso, Christiane Fernandes, Adolfo Horn, João Carlos de Aquino Almeida, Milton Masahiko Kanashiro

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

  1. Insight into Cytotoxic Potential ofPlants (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Trace elements and metal nanoparticles: mechanistic approaches to mitigating chemotherapy-induced toxicity-a review of literature evidence.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Leide Laura Figueiredo MacielLaboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes 28013-602, RJ, Brazil.
Marina Barreto SilvaLaboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes 28013-602, RJ, Brazil.
Rafaela Oliveira MoreiraCentro Federal de Educação Tecnológica, Nova Friburgo 28635-080, RJ, Brazil.
Ana Paula CardosoDepartamento de Química, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil.
Christiane FernandesDepartamento de Química, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil.
Adolfo HornDepartamento de Química, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil.ORCID 0000-0001-9155-9093
João Carlos de Aquino AlmeidaLaboratório de Fisiologia e Bioquímica de Microrganismos, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes 28013-602, RJ, Brazil.ORCID 0000-0002-4059-9930
Milton Masahiko KanashiroLaboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes 28013-602, RJ, Brazil.ORCID 0000-0002-5134-7341
State University of Norte Fluminense · BRUniversidade Federal de Santa Catarina · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26.010.100968/2018
6 · The paper itself

Abstract

Two platinum complexes [Pt(HL3)Cl]·H

Indexed as

antitumorapoptosisbreast cancer cellscytotoxicityplatinum(II) complexes

Identifiers

PMID36297448
PMCPMC9609024
OpenAlexW4297006181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.