Evidence map›Paper›PMID 36297378›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Halilibrahim Ciftci, Belgin Sever, Nilüfer Bayrak, Mahmut Yıldız, Hatice Yıldırım, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. NovelJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  6. Special Issue "Novel Anti-Proliferative Agents".Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Halilibrahim CiftciDepartment of Drug Discovery, Science Farm Ltd., Kumamoto 862-0976, Japan.ORCID 0000-0002-9796-7669
Belgin SeverMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.ORCID 0000-0003-4847-9711
Nilüfer BayrakDepartment of Chemistry, Faculty of Science, Istanbul University, Fatih, 34126 Istanbul, Turkey.
Mahmut YıldızChemistry Department, Gebze Technical University, Gebze, 41400 Kocaeli, Turkey.
Hatice YıldırımDepartment of Chemistry, Faculty of Engineering, Istanbul University-Cerrahpasa, Avcılar, 34320 Istanbul, Turkey.ORCID 0000-0003-3988-6120
Hiroshi TateishiMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.ORCID 0000-0003-1225-0720
Masami OtsukaDepartment of Drug Discovery, Science Farm Ltd., Kumamoto 862-0976, Japan.
Mikako FujitaMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.ORCID 0000-0001-6705-4052
Amaç Fatih TuYuNDepartment of Chemistry, Faculty of Science, Istanbul University, Fatih, 34126 Istanbul, Turkey.ORCID 0000-0001-5698-1109
Kumamoto University · JPFatih University · TRAnadolu University · TRGebze Technical University · TRIstanbul University-Cerrahpaşa · TRKoç University · TR

Funding

Istanbul University FBA-2016-20662
6 · The paper itself

Abstract

Colorectal cancer (CRC) and breast cancer are leading causes of death globally, due to significant challenges in detection and management. The late-stage diagnosis and treatment failures require the discovery of potential anticancer agents to achieve a satisfactory therapeutic effect. We have previously reported a series of plastoquinone analogues to understand their cytotoxic profile. Among these derivatives, three of them (

Indexed as

apoptosisbreast cancercolorectal cancercytotoxicityDNA bindinggrowth inhibitionNCI-60pharmacokinetic determinantsplastoquinone

Identifiers

PMID36297378
PMCPMC9609592
OpenAlexW4306398823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.