Evidence map›Paper›PMID 36297363›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

A Preclinical Study of an

Xiaohui Luan, Haoxi Zhou, Yimin Chen, Xiaojun Zhang, Mengchao Cui, Kuang Chen, Xiaodan Xu, Jinming Zhang, Baixuan Xu

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Lessons learned in application driven imaging agent design for image-guided surgery.European journal of nuclear medicine and molecular imaging · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaohui LuanChinese PLA General Hospital Chinese PLA Medical School, Beijing 100853, China.
Haoxi ZhouChinese PLA General Hospital Chinese PLA Medical School, Beijing 100853, China.
Yimin ChenKey Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID 0000-0002-1602-3253
Xiaojun ZhangDepartment of Nuclear Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Mengchao CuiKey Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
Kuang ChenChinese PLA General Hospital Chinese PLA Medical School, Beijing 100853, China.
Xiaodan XuDepartment of Nuclear Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Jinming ZhangDepartment of Nuclear Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Baixuan XuChinese PLA General Hospital Chinese PLA Medical School, Beijing 100853, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeProstate cancer (PCa) is characterized by high expression of prostate-specific 1membrane antigen (PSMA), a type II transmembrane protein. Prostate-specific membrane antigen positron emission tomography (PSMA PET) has high sensitivity and specificity and can therefore be potentially used to detect PCa. Exploiting the advantages of PSMA PET imaging, in this study, we aim to develop a novel radiopharmaceutical to facilitate biopsy punching of PCa.

methodsWe synthesized a high-affinity radiopharmaceutical of PSMA (

results

conclusionsThese results show that

Indexed as

125I-PSMA-7prostate cancerSPECT/CTtargeted biopsy

Identifiers

PMID36297363
PMCPMC9610460

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.