Evidence map›Paper›PMID 36297282›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

In Vitro Characterization of Inhibitors for Lung A549 and Leukemia K562 Cell Lines from Fungal Transformation of Arecoline Supported by In Silico Docking to M3-mAChR and ADME Prediction.

Amany E Ragab, Ebtisam T Badawy, Shaimaa M Aboukhatwa, Amal Kabbash, Kamilia A Abo El-Seoud

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cytotoxic activity ofJournal of advanced pharmaceutical technology & research
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Amany E RagabDepartment of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.ORCID 0000-0001-8276-5397
Ebtisam T BadawyDepartment of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.ORCID 0000-0002-5030-5609
Shaimaa M AboukhatwaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.ORCID 0000-0002-5013-7158
Amal KabbashDepartment of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
Kamilia A Abo El-SeoudDepartment of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
Tanta University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The search for anticancer drugs is of continuous interest. Arecoline is an alkaloid with anticancer activity. Herein, the metabolism of arecoline through fungal transformation was investigated for the discovery of potential anticancer drugs with higher activity and selectivity. Compounds

Indexed as

apoptosisarecolinefungal transformationleukemia K562lung A549M3-mAChR

Identifiers

PMID36297282
PMCPMC9609924
OpenAlexW4296642562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.