Evidence map›Paper›PMID 36297233›Full record

ArticlePathogens (Basel, Switzerland)2022

Targeting Host Tyrosine Kinase Receptor EPHA2 Signaling Affects Uropathogen Infection in Human Bladder Epithelial Cells.

Prema S Prakash, Alexander Kruse, Christian Vogel, Undraga Schagdarsurengin, Florian Wagenlehner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Macropinocytosis as a potential mechanism driving neurotropism ofFrontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Prema S PrakashClinic for Urology, Pediatric Urology and Andrology, Justus-Liebig-University, 35390 Giessen, Germany.ORCID 0000-0003-3391-5189
Alexander KruseClinic for Urology, Pediatric Urology and Andrology, Justus-Liebig-University, 35390 Giessen, Germany.ORCID 0000-0001-5526-9347
Christian VogelClinic for Urology, Pediatric Urology and Andrology, Justus-Liebig-University, 35390 Giessen, Germany.
Undraga SchagdarsurenginClinic for Urology, Pediatric Urology and Andrology, Justus-Liebig-University, 35390 Giessen, Germany.ORCID 0000-0003-0127-4938
Florian WagenlehnerClinic for Urology, Pediatric Urology and Andrology, Justus-Liebig-University, 35390 Giessen, Germany.ORCID 0000-0002-2909-0797
Justus-Liebig-Universität Gießen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary tract infections (UTIs) affect a major proportion of the world population but have limited non-antibiotic-based therapeutic and preventative strategies against UTIs. Facultative intracellular uropathogens such as strains of uropathogenic

Indexed as

bladder epithelial cellsEPHA2 inhibitionintracellular bacteriareceptor tyrosine kinasesurinary tract infectionsuropathogens

Identifiers

PMID36297233
PMCPMC9607038
OpenAlexW4304689552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.