Evidence map›Paper›PMID 36297159›Full record

ArticlePathogens (Basel, Switzerland)2022

Serendipitous Discovery of a Competitive Inhibitor of FraB, a

Pankajavalli Thirugnanasambantham, Sravya Kovvali, Austin Cool, Yuan Gao, Anice Sabag-Daigle, Erin F Boulanger, Mark Mitton-Fry, Angela Di Capua, Edward J Behrman, Vicki H Wysocki and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Pankajavalli ThirugnanasambanthamDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Sravya KovvaliDepartment of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
Austin CoolDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Yuan GaoDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Anice Sabag-DaigleDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210, USA.
Erin F BoulangerDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-3550-528X
Mark Mitton-FryDepartment of Medicinal Chemistry and Pharmacognosy, The Ohio State University, Columbus, OH 43210, USA.
Angela Di CapuaDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0001-6960-0715
Edward J BehrmanDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Vicki H WysockiDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Steffen LindertDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Brian M M AhmerDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-4267-7322
Venkat GopalanDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
The Ohio State University · US

Funding

Waters Select Series Cyclic IMS for P41 Native MS Resource Application to Alzheimer's DiseaseP41GM128577 · NIGMS · OHIO STATE UNIVERSITY · PI WYSOCKI, VICKI H. · 2018 to 2022
$7.6M
Salmonella-specific therapeuticsR01AI140541 · NIAID · OHIO STATE UNIVERSITY · PI AHMER, BRIAN M, GOPALAN, VENKAT · 2018 to 2021
$2.8M
NIAID NIH HHS R01 AI140541NIGMS NIH HHS P41 GM128577NIH HHS NIAID AI140541
6 · The paper itself

Abstract

Although salmonellosis, an infectious disease, is a significant global healthcare burden, there are no

Indexed as

competitive inhibitordrug discoverySalmonella deglycaseserendipity

Identifiers

PMID36297159
PMCPMC9609667
OpenAlexW4297547220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.