Evidence map›Paper›PMID 36297093›Full record

ArticleNutrients2022

A Health Care Professional Delivered Low Carbohydrate Diet Program Reduces Body Weight, Haemoglobin A1c, Diabetes Medication Use and Cardiovascular Risk Markers-A Single-Arm Intervention Analysis.

Grant D Brinkworth, Thomas P Wycherley, Pennie J Taylor, Campbell H Thompson

Open access · goldFull text read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Grant D BrinkworthCommonwealth Scientific and Industrial Research Organisation (CSIRO)-Health and Biosecurity, Westmead, NSW 2145, Australia.ORCID 0000-0001-9017-8395
Thomas P WycherleyAlliance for Research in Exercise, Nutrition and Activity, University of South Australia, Adelaide, SA 5000, Australia.ORCID 0000-0003-3096-1796
Pennie J TaylorCommonwealth Scientific and Industrial Research Organisation (CSIRO)-Health and Biosecurity, Westmead, NSW 2145, Australia.ORCID 0000-0001-8614-0829
Campbell H ThompsonDepartment of Medicine, University of Adelaide, Adelaide, SA 5000, Australia.ORCID 0000-0002-5164-3327
CSIRO Health and Biosecurity · AUThe University of Adelaide · AUUniversity of South Australia · AU

Funding

Diversa Health Pty Ltd. Corporate
6 · The paper itself

Abstract

This study examined the effectiveness of a health care professional delivered low-carbohydrate diet program (Diversa Health Program) aiming to improve obesity/type-2-diabetes management for people living in Australia. 511 adults (Age:57.1 ± 13.7 [SD] yrs) who participated between January 2017−August 2021 for ≥30 days with pre-post data collected for ≥1 key outcome variable (body weight and HbA1c) were included in the analysis. Average participation duration was 218 ± 207 days with 5.4 ± 3.9 reported consultation visits. Body weight reduced from 92.3 ± 23.0 to 86.3 ± 21.1 kg (n = 506, p < 0.001). Weight loss was 0.9 ± 2.8 kg (1.3%), 4.5 ± 4.3 kg (5.7%) and 7.9 ± 7.2 kg (7.5%), respectively, for those with a classification of normal weight (n = 67), overweight (n = 122) and obese (n = 307) at commencement. HbA1c reduced from 6.0 ± 1.2 to 5.6 ± 0.7% (n = 212, p < 0.001). For members with a commencing HbA1c of <5.7% (n = 110), 5.7−6.4% (n = 55), and ≥6.5% (n = 48), HbA1c reduced −0.1 ± 0.2%, −0.3 ± 0.3%, and −1.4 ± 1.3%, respectively. For members with a commencing HbA1c ≥6.5%, 90% experienced a HbA1c reduction and 54% achieved a final HbA1c < 6.5%. With inclusion and exclusion of metformin, respectively, 124 and 82 diabetes medications were prescribed to 63 and 42 members that reduced to 82 and 35 medications prescribed to 51 and 26 members at final visit. A health care professional delivered low-carbohydrate diet program can facilitate weight loss and improve glycaemic control with greatest improvements and clinical relevance in individuals with worse baseline parameters.

Indexed as

Cardiovascular DiseasesDiabetes MellitusDiabetes Mellitus, Type 2MetforminAdultBody WeightDiet, Carbohydrate-RestrictedGlycated HemoglobinHealth PersonnelHeart Disease Risk FactorsHumansInfantRisk FactorsWeight LossGlycated HemoglobinMetformindiabetesdietglycaemic controllifestyleweight loss

Identifiers

PMID36297093
PMCPMC9609895
OpenAlexW4306952281

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.