Evidence map›Paper›PMID 36297052›Full record

ArticleNutrients2022

Anti-Aging and Neuroprotective Properties of

Farida Tripodi, Ermelinda Falletta, Manuela Leri, Cristina Angeloni, Daniela Beghelli, Laura Giusti, Riccardo Milanesi, Belém Sampaio-Marques, Paula Ludovico, Lorenzo Goppa and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Acteoside exerts neuroprotective effects by preventing α-synuclein aggregation and oxidative stress in models of Parkinson's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  4. Utilizing amicroPublication biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Neuroprotective Terpenoids Derived fromInternational journal of molecular sciences · 2025
    Article
  9. Bioactive Polysaccharides fromMolecules (Basel, Switzerland) · 2025
    Review
  10. Foods (Basel, Switzerland) · 2025
    Article
  11. Review
  12. Article
  13. Effect of Solid-State Fermentation ofFoods (Basel, Switzerland) · 2024
    Article
  14. Biological Activities of Ethanol Extracts ofFoods (Basel, Switzerland) · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Extracts ofNutrition research and practice · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Farida TripodiDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0003-1246-979X
Ermelinda FallettaDepartment of Chemistry, University of Milano, 20133 Milano, Italy.ORCID 0000-0002-3127-8967
Manuela LeriDepartment of Experimental and Clinical Biomedical Sciences, University of Firenze, 50134 Firenze, Italy.ORCID 0000-0002-3785-0805
Cristina AngeloniDepartment for Life Quality Studies, Alma Mater Studiorum, University of Bologna, 47921 Rimini, Italy.ORCID 0000-0002-6731-6187
Daniela BeghelliSchool of Biosciences and Veterinary Medicine, University of Camerino, 62032 Camerino (MC), Italy.ORCID 0000-0002-4935-7874
Laura GiustiSchool of Pharmacy, University of Camerino, 62032 Camerino (MC), Italy.ORCID 0000-0001-7366-1932
Riccardo MilanesiDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0001-9925-2213
Belém Sampaio-MarquesLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-6580-0971
Paula LudovicoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0003-4130-7167
Lorenzo GoppaDepartment of Earth and Environmental Sciences (DSTA), University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-2333-2692
Paola RossiDepartment of Biology and Biotechnology "L. Spallanzani" (DBB), University of Pavia, 27100 Pavia, Italy.
Elena SavinoDepartment of Earth and Environmental Sciences (DSTA), University of Pavia, 27100 Pavia, Italy.
Monica BucciantiniDepartment of Experimental and Clinical Biomedical Sciences, University of Firenze, 50134 Firenze, Italy.ORCID 0000-0002-5243-9301
Paola CoccettiDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.
University of Milano-Bicocca · ITUniversity of Pavia · ITUniversità di Camerino · ITUniversity of Florence · ITUniversity of Minho · PTUniversity of Bologna · ITUniversity of Milan · IT

Funding

Fondazione Umberto Veronesi fellowshipItalian Ministry of University and Research (MUR) Dipartimenti di Eccellenza 2017Italian Ministry of University and Research (MUR) PhD fellowshiptalian Ministry of University and Research (MUR) Fondo di Ricerca e Giovani
6 · The paper itself

Abstract

Nutrition has relevant consequences for human health and increasing pieces of evidence indicate that medicinal mushrooms have several beneficial effects. One of the main issues in Western countries is represented by the challenges of aging and age-related diseases, such as neurodegenerative disorders. Among these, Parkinson's disease (PD) affects 10 million people worldwide and is associated with α-synuclein misfolding, also found in other pathologies collectively called synucleinopathies. Here, we show that aqueous extracts of two edible mushrooms,

Indexed as

AgaricalesAgingbeta-GlucansGrifolaalpha-SynucleinDrosophila melanogasterHeat-Shock ProteinsHumansProtein AggregatesReactive Oxygen SpeciesSaccharomyces cerevisiaealpha-Synucleinbeta-GlucansHeat-Shock ProteinsProtein AggregatesReactive Oxygen SpeciesDrosophila melanogasterGrifola frondosaHericium erinaceusmedicinal mushroomsParkinson’s disease (PD)Saccharomyces cerevisiaeα-synuclein

Identifiers

PMID36297052
PMCPMC9611596
OpenAlexW4306764858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.