ArticleNutrients2022
How a Family History of Allergic Diseases Influences Food Allergy in Children: The Japan Environment and Children's Study.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Maternal asthma during pregnancy and risks of allergy and asthma in progeny: A systematic review and meta-analysis.BJOG : an international journal of obstetrics and gynaecology · 2025Pooled it
- Prevalence of Immediate-Type Food Allergy and Food-Induced Anaphylaxis in Korean Schoolchildren.Allergy, asthma & immunology research · 2026Article
- Does Previous Anaphylaxis Determine Differences Between Patients Undergoing Oral Food Challenges to Cow's Milk and Hen's Egg?Nutrients · 2026Article
- Parental Age and Childhood Allergy Risk.JAMA network open · 2026Article
- Food allergen introduction practices and parent/caregiver attitudes based on family history of food allergy.Frontiers in allergy · 2025Article
- Prevalence and Impact of Food Allergies Among Jordanian Schoolchildren: A Comprehensive Analysis of Parent-Reported Data and Associated Atopic Conditions.International journal of pediatrics · 2025Article
- Analysis of heritability and environmental factors in preschool children with eczema: a case-control study.Scientific reports · 2024Article
- Skin and oral intervention for food allergy prevention based on dual allergen exposure hypothesis.Clinical and experimental pediatrics · 2024Article
- Baked Egg Oral Immunotherapy: Current State in Pediatric Age.Nutrients · 2024Review
- Article
- Prenatal Factors in the Development of Allergic Diseases.International journal of molecular sciences · 2024Review
- Feasibility and Safety of the Early Introduction of Allergenic Foods in Asian Infants with Eczema.Nutrients · 2024Article
- A survey on prevalence and parents' perceptions of food allergy in 3- to 16-year-old children in Wuhan, China.The World Allergy Organization journal · 2024Article
- Immune profiling of ART-conceived children in Kazakhstan: a case-control study.Frontiers in pediatrics · 2024Article
- Prevalence of Parent-Reported Food Allergy in a Mexican Pre-School Population.Journal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
The influence of family allergic history on food allergy in offspring in Japan is unknown. We analyzed data from a nationwide birth cohort study using logistic regression models to examine the associations of maternal, paternal, and both parental histories of allergic diseases (food allergy, atopic dermatitis, asthma, and rhinitis) with their child’s food allergy at 1.5 and 3 years of age. This analysis included 69,379 singleton full-term mothers and 37,179 fathers and their children. All parental histories of allergic diseases showed significant positive associations with their child’s food allergy. When both parents had a history of allergic diseases, the adjusted odds ratio (aOR) tended to be higher than when either parent had allergic diseases (p for trend < 0.0001). The highest aOR was detected when both parents had food allergy (2.60; 95% confidential interval, 1.58−4.27), and the aOR was 1.71 when either parent had food allergy (95% confidential interval, 1.54−1.91). The aORs were attenuated but still had significant positive associations after adjusting for the child’s atopic dermatitis, a risk factor for allergy development. In conclusion, all parental allergic diseases were significantly positively associated with their child’s food allergy. The effect of family history showed a stepwise increase in risk from either parent to both parents, and the highest risk of allergic disease was a parental history of food allergy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.