Evidence map›Paper›PMID 36296988›Full record

ArticleNutrients2022

Assessment of Iodine Concentration in Human Milk from Donors: Implications for Preterm Infants.

Noelia Ureta-Velasco, Kristin Keller, Diana Escuder-Vieco, José C E Serrano, Nadia Raquel García-Lara, Carmen R Pallás-Alonso

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Noelia Ureta-VelascoDepartment of Neonatology, 12 de Octubre University Hospital, Research Institute i+12, Complutense University of Madrid, 28041 Madrid, Spain.ORCID 0000-0001-8780-1836
Kristin Keller"Aladina-MGU"-Regional Human Milk Bank, 12 de Octubre University Hospital, Research Institute i+12, 28041 Madrid, Spain.
Diana Escuder-Vieco"Aladina-MGU"-Regional Human Milk Bank, 12 de Octubre University Hospital, Research Institute i+12, 28041 Madrid, Spain.
José C E SerranoDepartment of Experimental Medicine, Medicine Faculty, Lleida University, 25008 Lleida, Spain.ORCID 0000-0001-6714-6061
Nadia Raquel García-LaraDepartment of Neonatology, 12 de Octubre University Hospital, Research Institute i+12, Complutense University of Madrid, 28041 Madrid, Spain.ORCID 0000-0002-0541-3870
Carmen R Pallás-AlonsoDepartment of Neonatology, 12 de Octubre University Hospital, Research Institute i+12, Complutense University of Madrid, 28041 Madrid, Spain.ORCID 0000-0001-9710-8162
Universidad Complutense de Madrid · ESResearch Institute Hospital 12 de Octubre · ESUniversitat de Lleida · ES

Funding

Instituto de Salud Carlos III PI15/00995
6 · The paper itself

Abstract

Preterm infants are particularly vulnerable to developing iodine deficiency. Donor human milk (DHM) is the preferred feeding option if the mother’s own milk (MOM) is not available, but information on DHM iodine concentration (DHMIC) is lacking. Hence, we aimed to assess DHMIC to further evaluate the adequacy of iodine provision in preterm infants. Finally, associations that might influence DHMIC were studied. In 113 donors, we measured iodine intake by evaluating dietary records for five consecutive days with the DIAL® Software. From the second day of dietary record, donors provided human milk samples (at least one per day) for four consecutive days. Daily human milk samples were analyzed for DHMIC. A DHMIC ≥ 200 µg/L was considered an adequate iodine content for preterm infants. DHMIC and urine iodine concentration (UIC) were determined using ICP-MS. In our study, 83.2% of donors had a full-term infant. Breastfeeding time range was 1.5−49.4 months. During the dietary record, 55.8% took iodine-containing supplements, providing 40−200 µg/day of iodine. The medians (p25, p75) UIC and DHMIC were 112.4 (75.8, 160.1) and 148.5 (97.6, 206.1) µg/L, respectively. In this iodine-sufficient population, 70% had a DHMIC of <200 µg/L. Donors’ intake of iodine-containing supplements was associated with higher DHMIC.

Indexed as

IodineMilk, HumanBreast FeedingFemaleHumansInfantInfant, NewbornInfant, PrematureIodidesLactationIodidesIodinebreast milkdonor human milkhuman milk bankiodine in lactating womeniodine intakeSpainsupplementationurine iodine concentration

Identifiers

PMID36296988
PMCPMC9612023
OpenAlexW4306399051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.