Evidence map›Paper›PMID 36296983›Full record

Trial reportNutrients2022

Effects of

Keisuke Sakurai, Takayuki Toshimitsu, Erika Okada, Saya Anzai, Izumi Shiraishi, Noriko Inamura, Satoru Kobayashi, Toshihiro Sashihara, Tatsuhiro Hisatsune

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 5 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 5 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Efficacy and Safety ofNutrients · 2025
    Trial
  7. Trial
  8. Trial
  9. ProbioticNutrients · 2022
    Trial
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Keisuke SakuraiDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562, Japan.
Takayuki ToshimitsuFood Microbiology Research Laboratories, Applied Microbiology Research Department, Division of Research and Development, Meiji Co., Ltd., Hachiouji 192-0919, Japan.
Erika OkadaDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562, Japan.
Saya AnzaiDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562, Japan.
Izumi ShiraishiDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562, Japan.
Noriko InamuraUrban Design Center Kashiwanoha (UDCK), Kashiwa 277-0871, Japan.
Satoru KobayashiCommunity Health Promotion Laboratory, Mitsui Fudosan, Co., Ltd., Kashiwa 277-8519, Japan.
Toshihiro SashiharaFood Microbiology Research Laboratories, Applied Microbiology Research Department, Division of Research and Development, Meiji Co., Ltd., Hachiouji 192-0919, Japan.ORCID 0000-0001-7617-0987
Tatsuhiro HisatsuneDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8562, Japan.ORCID 0000-0002-8580-9874
The University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of probiotics is expected to be an intervention in neurodegenerative conditions that cause dementia owing to their ability to modulate neuroinflammatory responses via the microbiome-gut-brain axis. Therefore, we selected

Indexed as

Cognitive DysfunctionLactiplantibacillus plantarumMemoryProbioticsAgedDNA, RibosomalDouble-Blind MethodHumansInflammationInterleukin-10PowdersDNA, RibosomalInterleukin-10Powdersaginggut microbiotaLactiplantibacillusmemorymild cognitive impairmentprobiotics

Identifiers

PMID36296983
PMCPMC9610166
OpenAlexW4306398853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.