Evidence map›Paper›PMID 36296723›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis and Identification of New

Yaseen A M M Elshaier, Ashraf A Aly, Mohamed Abdel-Aziz, Hazem M Fathy, Alan B Brown, Stefan Bräse, Mohamed Ramadan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Yaseen A M M ElshaierOrganic and Medicinal Chemistry Department, Faculty of Pharmacy, University of Sadat City, Menoufia 32958, Egypt.ORCID 0000-0003-4332-6345
Ashraf A AlyDepartment of Chemistry, Faculty of Science, Minia University, El-Minia 61519, Egypt.ORCID 0000-0002-0314-3408
Mohamed Abdel-AzizMedicinal Chemistry Department, Faculty of Pharmacy, Minia University, El-Minia 61519, Egypt.
Hazem M FathyPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assuit 71524, Egypt.
Alan B BrownChemistry Department, Florida Institute of Technology, Melbourne, FL 32901, USA.
Stefan BräseInstitute of Organic Chemistry, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.ORCID 0000-0003-4845-3191
Mohamed RamadanPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assuit 71524, Egypt.
Al-Azhar University · EGMinia University · EGFlorida Institute of Technology · USKarlsruhe Institute of Technology · DEUniversity of Sadat City · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthesis of thiazolidinone based on quinolone moiety was established starting from 4-hydroxyquinol-2-ones. The strategy started with the reaction of ethyl bromoacetate with 4-hydroxyquinoline to give the corresponding ethyl oxoquinolinyl acetates, which reacted with hydrazine hydrate to afford the hydrazide derivatives. Subsequently, hydrazides reacted with isothiocyanate derivatives to give the corresponding

Indexed as

QuinolonesUreaseAnti-Bacterial AgentsEnzyme InhibitorsHydrazinesHydroxamic AcidsIsothiocyanatesLigandsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipThioureaacetohydroxamic acidAnti-Bacterial AgentsEnzyme InhibitorsHydrazinesHydroxamic AcidsIsothiocyanatesLigandsQuinolonesThioureaUreasedialkyl acetylenedicarboxylatesin vitro urease inhibition propertiesmolecular dockingN,N-disubstituted thioureasthiazolidinones

Identifiers

PMID36296723
PMCPMC9608620
OpenAlexW4307272932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.